Small insertions and deletions (ID) Signatures

Small insertions and deletions (ID), also known as indels, are defined as the incorporation or loss of small fragments of DNA (usually between 1 and 50 base pairs) in a specific genomic location.

Although there is no single intuitive and naturally constrained set of ID mutation types (as there arguably are for single base substitutions and doublet base substitutions), a compilation of 83 different types considering size, nucleotides affected and presence on repetitive and/or microhomology regions was used to extract mutational signatures. It can be found here.

Click on any signature below to learn more about its details.