COSMIC Mutational Signatures Data Files

Download current and previous releases of COSMIC mutational signatures here.

Files are organized by release, genome, and mutation type. Once you have selected the version that you would like to download, click the highlighted text by the download icon to save the file to your computer.

Each file is tab separated and the rows are the mutational contexts and the columns are the reference signatures. Each column sums to one and the values in each column are the contributions of the mutational context to that signature.

v3.2 - March 2021

GRCh37
Homo sapiens
 SBS  DBS
GRCh38
Homo sapiens
 SBS  DBS
mm9
Mus musculus
 SBS  DBS
mm10
Mus musculus
 SBS  DBS
rn6
Rattus norvegicus
 SBS  DBS
 ID  (derived from GRCh37, no renormalization available)

v3.1 - June 2020

GRCh37
Homo sapiens
 SBS  DBS
GRCh38
Homo sapiens
 SBS  DBS
mm9
Mus musculus
 SBS  DBS
mm10
Mus musculus
 SBS  DBS
rn6
Rattus norvegicus
 SBS  DBS
 ID  (derived from GRCh37, no renormalization available)

v3.0 - May 2019

GRCh37
Homo sapiens
 SBS  DBS
GRCh38
Homo sapiens
 SBS  DBS
mm9
Mus musculus
 SBS  DBS
mm10
Mus musculus
 SBS  DBS
rn6
Rattus norvegicus
 SBS  DBS
 ID  (derived from GRCh37, no renormalization available)

v2.0 - March 2015

GRCh37
Homo sapiens
 SBS
GRCh38
Homo sapiens
 SBS
mm9
Mus musculus
 SBS
mm10
Mus musculus
 SBS
rn6
Rattus norvegicus
 SBS

v1.0 - August 2013

GRCh37
Homo sapiens
 SBS
GRCh38
Homo sapiens
 SBS
mm9
Mus musculus
 SBS
mm10
Mus musculus
 SBS
rn6
Rattus norvegicus
 SBS