This tab shows an overview of the mutation data [more details]
Gene Name:
FBXW7_NM_018315_2
Mutation Id:
COSM74637
AA Mutation:
p.R425C (Substitution - Missense, position 425, RC)
CDS Mutation:
c.1273C>T (Substitution, position 1273, CT)
GRCh38:
4:152326137..152326137, view Ensembl Contig
COSMIC Genome Browser:
4:152326137..152326137, view in COSMIC JBrowse
Ever confirmed somatic:
Yes
FATHMM prediction:
Pathogenic (score 0.94)
This tab displays the distribution of mutated samples and tissue types. [more details]
This tab displays a table of muated samples, with tissue, histology and zygosity information. Publication information is also included, where available, with links to PUBMED. [more details]
Sample name Gene name Transcript Primary Tissue Histology Pubmed ID Zygosity Somatic Status Sample Source LOH Resistant Mutation Drugs
This tab displays a table of pathways affected by the mutation [more details]
SourcePathways
WikiPathwayDelta-Notch Signaling Pathway
This tab displays a table of references for the mutation [more details]
Reference Title Author Year Journal Status COSMIC Pubmed