Cosmic » Mutation » Overview » APCS » p.G141S / c.421G>A
Overview
This tab shows an overview of the mutation data [more details]
- Description:
- Mutation id:
- AA Mutation:
- CDS Mutation:
- NCBI 36:
- GRCH 37:
- Cancer Genome Browser:
- CDD:
- Homologene:
- Ever confirmed somatic:
- APCS
- COSM33492
- p.G141S ( Substitution - Missense )
- c.421G>A ( Substitution )
- Ensembl Contig View: 1: 157824871..157824871
- Ensembl Contig View: 1: 159558247..159558247
- COSMIC GBrowse: 1: 159558247..159558247
- NP_001630.1
- 110951 , click here to look the multiple sequence alignment.
- Yes
Tissue Distribution
This tab displays the distribution of mutated samples and tissue types.
[more details]
Samples
This tab displays a table of muated samples, with tissue, histology and zygosity information.
Publication information is also included, where available, with links to PUBMED.
[more details]
| Sample name | Gene Name | Transcript | Primary Tissue | Histology | Pubmed Id | Zygosity | Somatic Status |
|---|
Protein features
This tab displays a table of protein features
[more details]
| View | Identifier | Source | Feature | Start | End | Status | Score |
|---|---|---|---|---|---|---|---|
| PF00354 | Pfam | Pentaxin:26-219 | 26 | 219 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :Pentaxin:26-219( 26- 219 ) | |||||||
| P02743 | G3DSA:2.60.120.200 | G3DSA:2.60.120.200 | 22 | 219 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :G3DSA:2.60.120.200( 22- 219 ) | |||||||
| P02743 | Pentaxin | Pentaxin | 26 | 219 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :Pentaxin( 26- 219 ) | |||||||
| P02743 | PENTAXIN | PENTAXIN | 138 | 157 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :PENTAXIN( 138- 157 ) | |||||||
| P02743 | PTHR19277:SF7 | PTHR19277:SF7 | 1 | 223 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :PTHR19277:SF7( 1- 223 ) | |||||||
| P02743 | PTHR19277 | PTHR19277 | 1 | 223 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :PTHR19277( 1- 223 ) | |||||||
| P02743 | PTX | PTX | 20 | 223 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :PTX( 20- 223 ) | |||||||
| P02743 | ConA_like_lec_gl | ConA_like_lec_gl | 20 | 223 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :ConA_like_lec_gl( 20- 223 ) | |||||||
| P02743 | UniProt:curator | Serum amyloid P-component | 20 | 223 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :Serum amyloid P-component( 20- 223 ) | |||||||
| P02743 | UniProt:curator | Serum amyloid P-component(1-203) | 20 | 222 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :Serum amyloid P-component(1-203)( 20- 222 ) | |||||||
| P02743 | UniProt:curator | Pentaxin | 20 | 223 | Overlap | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :Pentaxin( 20- 223 ) | |||||||
| P02743 | PubMed:16959974 | UNIPROTKB_P02743_VARIANT_141_141 | 141 | 141 | Proximity | 100.00 | |
|
APCS MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
P02743 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS 60
APCS DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
P02743 DLSRAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWESS 120
APCS SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
P02743 SGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWD 180
APCS SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
P02743 SVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
More detailsWildtype Residue : G Mutant Position : 141 Mutant label : p.G141S Feature Name :UNIPROTKB_P02743_VARIANT_141_141( 141- 141 ) | |||||||
References
This tab displays a table of references for the mutation
[more details]
| Reference Title | Author | Year | Journal | Status | COSMIC | Pubmed |
|---|