Cosmic » Mutation » Overview » RNF135 »p.Q226H / c.678G>T

This tab shows an overview of the mutation data [more details]
Gene Name:
RNF135
Mutation Id:
COSM184101
AA Mutation:
p.Q226H ( Substitution - Missense )
CDS Mutation:
c.678G>T ( Substitution )
GRCh37:
Ensembl Contig View 17:29315118..29315128
Cancer Genome Browser:
COSMIC GBrowse 17:29315118..29315128
CDD:
NP_922921.1
Ever confirmed somatic:
Yes
This tab displays the distribution of mutated samples and tissue types. [more details]
This tab displays a table of muated samples, with tissue, histology and zygosity information. Publication information is also included, where available, with links to PUBMED. [more details]
Sample name Gene name Transcript Primary Tissue Histology Pubmed ID Zygosity Somatic Status
This tab displays a table of protein features [more details]
View Identifier Source Feature Start End Status Score
Q8IUD6 UniProt:curator E3 ubiquitin-protein ligase RNF135 1 432 Overlap 100.00
RNF135 MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60 Q8IUD6 MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60 RNF135 TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP 120 Q8IUD6 TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP 120 RNF135 ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDL 180 Q8IUD6 ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDL 180 RNF135 SMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPL 240 Q8IUD6 SMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPL 240 RNF135 PDQSHPALRRASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTS 300 Q8IUD6 PDQSHPALRRASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTS 300 RNF135 QVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQLSAW 360 Q8IUD6 QVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQLSAW 360 RNF135 HMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLH 420 Q8IUD6 HMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLH 420 RNF135 PGNYLIIKQVKV Q8IUD6 PGNYLIIKQVKV

More details

Wildtype Residue : Q Mutant Position : 226 Mutant label : p.Q226H Feature Name :E3 ubiquitin-protein ligase RNF135( 1- 432 )
Q8IUD6 UniProt:curator UNIPROTKB_Q8IUD6_VAR_SEQ_211_432 211 432 Overlap 100.00
RNF135 MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60 Q8IUD6 MAGLGLGSAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACP 60 RNF135 TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP 120 Q8IUD6 TCRQGAAQQPHLRKNTLLQDLADKYRRAAREIQAGSDPAHCPCPGSSSLSSAAARPRRRP 120 RNF135 ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDL 180 Q8IUD6 ELQRVAVEKSITEVAQELTELVEHLVDIVRSLQNQRPLSESGPDNELSILGKAFSSGVDL 180 RNF135 SMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPL 240 Q8IUD6 SMASPKLVTSDTAAGKIRDILHDLEEIQEKLQESVTWKEAPEAQMQGELLEAPSSSSCPL 240 RNF135 PDQSHPALRRASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTS 300 Q8IUD6 PDQSHPALRRASRFAQWAIHPTFNLKSLSCSLEVSKDSRTVTVSHRPQPYRWSCERFSTS 300 RNF135 QVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQLSAW 360 Q8IUD6 QVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSRDQVLGRTMDSCCVEWKGTSQLSAW 360 RNF135 HMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLH 420 Q8IUD6 HMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEKLLYECTISASSPLYPAFWLYGLH 420 RNF135 PGNYLIIKQVKV Q8IUD6 PGNYLIIKQVKV

More details

Wildtype Residue : Q Mutant Position : 226 Mutant label : p.Q226H Feature Name :UNIPROTKB_Q8IUD6_VAR_SEQ_211_432( 211- 432 )
This tab displays a table of references for the mutation [more details]
Reference Title Author Year Journal Status COSMIC Pubmed