Mutation Overview - CARD17 - p.P109L(Substitution - Missense)

Cosmic » Mutation » Overview » CARD17 » p.P109L / c.326C>T

Overview

This tab shows an overview of the mutation data [more details]
  • Description:
  • Mutation id:
  • AA Mutation:
  • CDS Mutation:
  • GRCH 37:
  • Cancer Genome Browser:
  • CDD:
  • Ever confirmed somatic:

Tissue Distribution

This tab displays the distribution of mutated samples and tissue types. [more details]

Samples

This tab displays a table of muated samples, with tissue, histology and zygosity information. Publication information is also included, where available, with links to PUBMED. [more details]
Sample name Gene Name Transcript Primary Tissue Histology Pubmed Id Zygosity Somatic Status

Protein features

This tab displays a table of protein features [more details]
View Identifier Source Feature Start End Status Score
Q5XLA6 UniProt:curator Caspase recruitment domain-containing protein 17 1 110 Overlap 100.00
CARD17 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS 60 Q5XLA6 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS 60 CARD17 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS Q5XLA6 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS

More details

Wildtype Residue : P Mutant Position : 109 Mutant label : p.P109L Feature Name :Caspase recruitment domain-containing protein 17( 1- 110 )

Pathways Affected

This tab displays a table of pathways affected by the mutation [more details]
Source Pathways
Reactome
WikiPathway Androgen Receptor Signaling Pathway
WikiPathway NOD pathway
WikiPathway Apoptosis
WikiPathway MAPK signaling pathway

References

This tab displays a table of references for the mutation [more details]
Reference Title Author Year Journal Status COSMIC Pubmed