This tab shows a graphical representation of the selected gene in JBrowse and a general overview of the information available for the gene. [more details]
Gene name
TP53
This is a known cancer gene, for more information please look here
Genomic Coordinates
17:7572927..7590856
Gene Id
COSG501
Synonyms
LFS1,P53,TRP53,p53,CCDS11118.1,P04637,ENSG00000141510
Drug Sensitivity Data:
Mutations in TP53 are associated with altered sensitivity to the following drug(s) : Imatinib, AZD-0530, GNF-2, Epothilone B, AICAR, Docetaxel, Methotrexate, CCT018159, Nutlin-3a, Etoposide, GNF-2, Epothilone B, Thapsigargin, OSU-03012, Nutlin-3a
Click here for all TP53 drug sensitivity data
No.of Samples
Total number of unique samples: 97717
Unique samples with mutations: 26293
Alternative Transcripts
TP53_ENST00000545858, TP53_ENST00000269305, TP53_ENST00000455263, TP53_ENST00000414315, TP53_ENST00000413465, TP53_ENST00000420246
cDNA Sequence
ENST00000269305
Protein Sequence
TP53
Transcript and Protein Aligned
ENST00000269305+TP53
This tab shows gene fusions involving the selected gene. [more details]

No Fusions reported for TP53

This tab shows studies associated with the selected gene. [more details]
This tab shows publications associated with the selected gene. [more details]
Reference Title Author Year Journal Status COSMIC Pubmed

Further details and experimental information for the references describing these data are available at the IARC TP53 Database

Cosmic Genome Browser

Mutation Analysis

Distribution

histogram image

External Links

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