This tab shows a graphical representation of the selected gene in JBrowse and a general overview of the information available for the gene. [more details]
Gene name
SMAD4
This is a known cancer gene, for more information please look here
Genomic Coordinates
18:48573417..48604837
Gene Id
COSG925
Synonyms
DPC4,JIP,MADH4,CCDS11950.1,Q13485,Q9BYG6,ENSG00000141646
Drug Sensitivity Data:
Mutations in SMAD4 are associated with altered sensitivity to the following drug(s) : Lapatinib, A-443654, Erlotinib, 17-AAG, Dasatinib, Paclitaxel, VX-680, WZ-1-84, BI-2536, A-443654, AZD-0530, Erlotinib, Paclitaxel, WZ-1-84, Lapatinib, BIBW2992, RO-3306, 17-AAG, BMS-708163
Click here for SMAD4 all drug sensitivity data
No.of Samples
Total number of unique samples: 25870
Unique samples with mutations: 806
Alternative Transcripts
SMAD4_ENST00000452201
cDNA Sequence
ENST00000342988
Protein Sequence
SMAD4
Transcript and Protein Aligned
ENST00000342988+SMAD4
This tab shows gene fusions involving the selected gene. [more details]

No Fusions reported for SMAD4

This tab shows studies associated with the selected gene. [more details]
This tab shows publications associated with the selected gene. [more details]
Reference Title Author Year Journal Status COSMIC Pubmed

Cosmic Genome Browser

Mutation Analysis

Distribution

histogram image

External Links