This tab shows a graphical representation of the selected gene in JBrowse and a general overview of the information available for the gene. [more details]
Gene name
PTEN
This is a known cancer gene, for more information please look here
Genomic Coordinates
10:89624227..89725229
Gene Id
COSG15
Synonyms
BZS,MGC11227,MHAM,MMAC1,PTEN1,P60484,ENSG00000171862
Drug Sensitivity Data:
Mutations in PTEN are associated with altered sensitivity to the following drug(s) : Bosutinib, BMS-754807, OSI-906, AZD8055, Temsirolimus, AZD6482, 17-AAG, MK-2206, BIBW2992, TGX221, MK-2206, GDC0941, AZD6482, KU-55933, BIBW2992, AZD8055, Methotrexate, Bosutinib, BMS-754807, OSI-906
Click here for all PTEN drug sensitivity data
No.of Samples
Total number of unique samples: 45239
Unique samples with mutations: 3132
Mouse mutagenesis
Mouse insertional mutagenesis experiments support PTEN as a cancer causing gene, please click
for more information.
cDNA Sequence
ENST00000371953
Protein Sequence
PTEN
Transcript and Protein Aligned
ENST00000371953+PTEN
This tab shows gene fusions involving the selected gene. [more details]

No Fusions reported for PTEN

This tab shows studies associated with the selected gene. [more details]
This tab shows publications associated with the selected gene. [more details]
Reference Title Author Year Journal Status COSMIC Pubmed

Cosmic Genome Browser

Mutation Analysis

Distribution

histogram image

External Links