This tab shows a graphical representation of the selected gene in JBrowse and a general overview of the information available for the gene. [more details]
Gene name
KRAS
This is a known cancer gene, for more information please look here
Genomic Coordinates
12:25362729..25403865
Gene Id
COSG4
Synonyms
C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3 ... [more]
... RASK2, CCDS8702.1, P01116
Drug Sensitivity Data:
Mutations in KRAS are associated with altered sensitivity to the following drug(s) : FH535, Epothilone B, RDEA119, CI-1040, BMS-754807, JNK-9L, OSI-906, PF-562271, AUY922, Bryostatin 1, PD-0325901, AZD6244, PD-173074, BX-795, BI-D1870, Vorinostat, KU-55933, A-769662, Temsirolimus, AZD-2281, Camptothecin, Bosutinib, Axitinib, AZD6482, Docetaxel, ATRA, Gefitinib, JNJ-26854165, TW 37, MK-2206, AG-014699, NVP-BEZ235, GDC0941, AZD8055, WO2009093972, ZM-447439, Z-LLNle-CHO, AZ628, Z-LLNle-CHO, AZ628, AZD6244, PD-0325901, ZM-447439, FH535, RDEA119, CI-1040, JNK-9L, BMS-754807, OSI-906, TW 37, PD-173074, NVP-BEZ235, AZD8055, AZD6482, GDC0941, BX-795, Methotrexate, Vorinostat, Temsirolimus, AZD6482, Axitinib
Click here for KRAS all drug sensitivity data
No.of Samples
Total number of unique samples: 155072
Unique samples with mutations: 30638
Alternative Transcripts
KRAS_ENST00000256078
cDNA Sequence
ENST00000311936
Protein Sequence
KRAS
Transcript and Protein Aligned
ENST00000311936+KRAS
This tab shows gene fusions involving the selected gene. [more details]
KRAS is involved in fusions with :
UBE2L3 ( 1 mutations in 1 samples )
This tab shows studies associated with the selected gene. [more details]
This tab shows publications associated with the selected gene. [more details]
Reference Title Author Year Journal Status COSMIC Pubmed

Cosmic Genome Browser

Mutation Analysis

Distribution

histogram image

External Links