Cosmic » Gene » Overview » BRAF
This tab shows a graphical representation of the selected gene in GBrowse and a general
overview of the information available for the gene.
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- Gene name
- BRAF
- Gene Id
- COSG2
- Synonyms
- B-raf 1,B-raf1,BRAF1,MGC126806,MGC138284,RAFB1,CCDS5863.1,P15056,ENSG00000157764
- Genomic Summary
- Drug Sensitivity Data:
- Click here for BRAF drug sensitivity data
Mutations in BRAF are associated with altered sensitivity to the following drug(s) :
Inceased sensitivity: PF-562271, CEP-701, FTI-277, 17-AAG, PD-0325901, SB590885, AZD6244, PD-173074, ZM-447439, BIBW2992, Temsirolimus, Metformin, AZD6482, Gefitinib, PLX4720, Nutlin-3a, AZ628, Bortezomib, Embelin, RDEA119, FH535, CI-1040, CHIR-99021, AP-24534, Obatoclax Mesylate - No.of Samples
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Total number of unique samples: 158334
Unique samples with mutations: 31138
This tab displays the COSMIC Cancer Genome Browser.
COSMIC data can be viewed in genomic conext.
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This tab shows sequence data for the selected gene.
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- cDNA Sequence
- NM_004333
- Protein Sequence
- BRAF
- Transcript and Protein Aligned
- NM_004333+BRAF
This tab shows gene fusions involving the selected gene.
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AKAP9_ENST00000356239 ( 4 mutations in 292 samples )
FAM131B_ENST00000443739 ( 3 mutations in 9 samples )
FCHSD1 ( 1 mutations in 2 samples )
KIAA1549 ( 439 mutations in 1055 samples )
SLC45A3 ( 1 mutations in 6 samples )
This tab shows publications associated with the selected gene.
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| Reference Title | Author | Year | Journal | Status | COSMIC | Pubmed |
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