This tab shows a graphical representation of the selected gene in JBrowse and a general overview of the information available for the gene. [more details]
Gene name
BRAF
This is a known cancer gene, for more information please look here
Gene Id
COSG2
Synonyms
B-raf 1,B-raf1,BRAF1,MGC126806,MGC138284,RAFB1,CCDS5863.1,P15056,ENSG00000157764
Drug Sensitivity Data:
Mutations in BRAF are associated with altered sensitivity to the following drug(s) : Nutlin-3a, PLX4720, AZ628, Bortezomib, Embelin, RDEA119, FH535, CI-1040, CHIR-99021, AP-24534, Obatoclax Mesylate, PF-562271, CEP-701, FTI-277, 17-AAG, PD-0325901, SB590885, AZD6244, PD-173074, ZM-447439, BIBW2992, Temsirolimus, Metformin, AZD6482, Gefitinib
Click here for BRAF all drug sensitivity data
No.of Samples
Total number of unique samples: 187951
Unique samples with mutations: 36590
cDNA Sequence
ENST00000288602
Protein Sequence
BRAF
Transcript and Protein Aligned
ENST00000288602+BRAF
This tab shows gene fusions involving the selected gene. [more details]
BRAF is involved in fusions with :
AGTRAP ( 1 mutations in 1 samples )
AKAP9_ENST00000356239 ( 4 mutations in 292 samples )
CLCN6 ( 1 mutations in 96 samples )
FAM131B_ENST00000443739 ( 4 mutations in 105 samples )
FCHSD1 ( 1 mutations in 2 samples )
GNAI1 ( 1 mutations in 96 samples )
KIAA1549 ( 582 mutations in 1289 samples )
MKRN1 ( 1 mutations in 96 samples )
RNF130 ( 2 mutations in 96 samples )
SLC45A3 ( 1 mutations in 6 samples )
This tab shows studies associated with the selected gene. [more details]
This tab shows publications associated with the selected gene. [more details]
Reference Title Author Year Journal Status COSMIC Pubmed

Cosmic Genome Browser

Mutation Analysis

Distribution

histogram image

External Links