GRCh38 · COSMIC v95

Overview

This inferred breakpoint table displays a list of all inferred breakpoints derived from a number of expressed gene fusion mRNA variants. You can see more information on the help pages.

Genes
EML4 - ALK

Mutation ID 5' Partner Gene 3' Partner Gene No. of Mutations Mutation Frequency
Gene Name Last Observed Exon Inferred Breakpoint Inserted Sequence Gene Name First Observed Exon Inferred Breakpoint Inserted Sequence
COSF408 EML4 13 1_1751 - ALK 20 4080_6220 - 182 25.28%
COSF474 EML4 6 1_929+220 - ALK 20 4080_6220 - 99 13.75%
COSF409 EML4 20 1_2504 - ALK 20 4080_6220 - 51 7.08%
COSF411 EML4 6 1_929 - ALK 20 4080_6220 - 36 5%
COSF488 EML4 18 1_2318+654_insT y ALK 20 4080-172_6220 - 4 .56%
COSF487 EML4 18 1_2318 - ALK 20 4080_6220 - 3 .42%
COSF479 EML4 2 1_470 - ALK 20 4080-117_6220 - 2 .28%
COSF475 EML4 15 1_2029 - ALK 20 4080_6220 - 2 .28%
COSF1544 EML4 6 1_929 - ALK 20 4080-18_6220 - 2 .28%
COSF1065 EML4 14 1_1903 - ALK 20 4080_6220 - 2 .28%
COSF489 EML4 13 1_1751+447 - ALK 20 4080-161_6220 - 1 .14%
COSF490 EML4 20 1_2504+182 - ALK 20 4080-67_6220 - 1 .14%
COSF491 EML4 14 1_1903_insATATGCTGGAT y ALK 20 4129_6220 - 1 .14%
COSF493 EML4 6 1_929+805_insAA y ALK 20 4080-115_6220 - 1 .14%
COSF730 EML4 20 1_2504 - ALK 20 4080-18_6220 - 1 .14%
COSF732 EML4 17 1_2229_ins68 y ALK 20 4080_6220 - 1 .14%
COSF1062 EML4 13 1_1751 - ALK 20 4080-69_6220 - 1 .14%
COSF1296 EML4 6 1_929 - ALK 19 3975_6220 - 1 .14%
COSF1368 EML4 17 1_2229+2522 - ALK 20 4126_6220 - 1 .14%
COSF1539 EML4 13 1_1751 - ALK 20 4080-90_6220 - 1 .14%
COSF1541 EML4 14 1_1903 - ALK 20 4080-123_6220 - 1 .14%
COSF478 EML4 2 1_470 - ALK 20 4080_6220 - 1 .14%
COSF476 EML4 6 1_929+(7320) - ALK 20 4080_6220 - 1 .14%
COSF410 EML4 13 1_1751+1485 - ALK 20 4080-1254_6220 - 1 .14%
COSF414 EML4 13 1_1751+2575 - ALK 20 4080-203_6220 - 1 .14%
COSF462 EML4 13 1_1751+(3600) - ALK 20 4080-297_6220 - 1 .14%
COSF464 EML4 20 1_2504+545 - ALK 20 4080-232_6220 - 1 .14%
COSF473 EML4 ? ? - ALK ? ? - 320 44%
Total Mutations720100%

Tissues

Tissue based mutation frequency for all breakpoints. You can see more information on the help pages.

Primary Tissue Mutated Samples All Samples % Mutated

References

Detailed list of all the papers where this fusion has been reported. You can see more information on the help pages.

Reference Title Author Year Journal Status COSMIC Pubmed