lipid phosphatase, modulator of the PI3K/AKT pathway, catalyses dephosphorylation of phosphatidylinositol-3,4,5-trisphosphate, a key molecule involved in cell growth signalling, specifically at the 3 position on the inositol ring [Pubmed]; can dephosphorylate protein substrates on serine/threonine and tyrosine residues [Pubmed]; regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms [Pubmed]