EWSR1

Ewing sarcoma breakpoint region 1 (EWS)

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function summary function summary

transcriptional activator of c-fos, ErbB2, Xvent-2 [Pubmed]; depletion results in alternative splicing changes of genes involved in DNA repair and genotoxic stress signaling, including ABL1, CHEK2, and MAP4K2, which reduces cell viability and proliferation upon UV irradiation [Pubmed]

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