AMER1

APC membrane recruitment protein 1

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function summary function summary

binds to the tumour suppressor APC and acts as an inhibitor of Wnt signalling by inducing beta-catenin degradation [Pubmed]; inhibits the ubiquitination of NRF2; AMER1 and NRF2 compete for binding to KEAP1 [Pubmed]; enhances p53 acetylation by CBP/p300 [Pubmed]

Suppresses Gene name Field Field Promotes