GRCh38 · COSMIC v95

Summary

This section shows a summary for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the Sanger Institute Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.

Study
ICGC (GACA-CN) : Gastric Cancer - CN
Study ID
COSU371
Description
ICGC Project Summary:
In view of its high prevalence in China and the existence of possible interacting environmental factors, China will focus on gastric cancer as a part of the International Cancer Genome Consortium activities. In particular, China will focus both on Intestinal-type and diffuse-type cancer. The major reasons for selection of gastric cancer are:
  • It is the most common cancer with high incidence and poor prognosis in China, most of cancer patients to be diagnostic too later to cure.
  • Intestinal- type and diffuse-type cancer is different in clinical pathological features and gene expression profiling.
  • About 50-80% of cancers have the high risk of recurrence and metastasis following creative resection.
  • Precancerous lesion including intestinal metaplasia (IM) and dysplasia (Dys) has high incidence and have a high risk to be transformed to malignance.
  • It is fundamental to analyze genomic changes for discovering biomarkers to detect gastric cancer early and to predict prognosis.