Mutational Signatures (v3.1 - June 2020)

Small Insertion and Deletion (ID) Signatures

Small insertions and deletions (ID), also known as indels, are defined as the incorporation or loss of small fragments of DNA (usually between 1 and 50 base pairs) in a specific genomic location.

Although there is no single intuitive and naturally constrained set of ID mutation types (as there arguably are for single base substitutions and doublet base substitutions), a compilation of 83 different types considering size, nucleotides affected and presence on repetitive and/or microhomology regions was used to extract mutational signatures. It can be found here.

Click on any signature below to learn more about its details.