TYK2 ATG CCT CTG CGC CAC TGG GGG ATG GCC AGG GGC AGT AAG CCC GTT GGG GAT GGA GCC CAG 60 M P L R H W G M A R G S K P V G D G A Q 20 CCC ATG GCT GCC ATG GGA GGC CTG AAG GTG CTT CTG CAC TGG GCT GGT CCA GGC GGC GGG 120 P M A A M G G L K V L L H W A G P G G G 40 GAG CCC TGG GTC ACT TTC AGT GAG TCA TCG CTG ACA GCT GAG GAA GTC TGC ATC CAC ATT 180 E P W V T F S E S S L T A E E V C I H I 60 GCA CAT AAA GTT GGT ATC ACT CCT CCT TGC TTC AAT CTC TTT GCC CTC TTC GAT GCT CAG 240 A H K V G I T P P C F N L F A L F D A Q 80 GCC CAA GTC TGG TTG CCC CCA AAC CAC ATC CTA GAG ATC CCC AGA GAT GCA AGC CTG ATG 300 A Q V W L P P N H I L E I P R D A S L M 100 CTA TAT TTC CGC ATA AGG TTT TAT TTC CGG AAC TGG CAT GGC ATG AAT CCT CGG GAA CCG 360 L Y F R I R F Y F R N W H G M N P R E P 120 GCT GTG TAC CGT TGT GGG CCC CCA GGA ACC GAG GCA TCC TCA GAT CAG ACA GCA CAG GGG 420 A V Y R C G P P G T E A S S D Q T A Q G 140 ATG CAA CTC CTG GAC CCA GCC TCA TTT GAG TAC CTC TTT GAG CAG GGC AAG CAT GAG TTT 480 M Q L L D P A S F E Y L F E Q G K H E F 160 GTG AAT GAC GTG GCA TCA CTG TGG GAG CTG TCG ACC GAG GAG GAG ATC CAC CAC TTT AAG 540 V N D V A S L W E L S T E E E I H H F K 180 AAT GAG AGC CTG GGC ATG GCC TTT CTG CAC CTC TGT CAC CTC GCT CTC CGC CAT GGC ATC 600 N E S L G M A F L H L C H L A L R H G I 200 CCC CTG GAG GAG GTG GCC AAG AAG ACC AGC TTC AAG GAC TGC ATC CCG CGC TCC TTC CGC 660 P L E E V A K K T S F K D C I P R S F R 220 CGG CAT ATC CGG CAG CAC AGC GCC CTG ACC CGG CTG CGC CTT CGG AAC GTC TTC CGC AGG 720 R H I R Q H S A L T R L R L R N V F R R 240 TTC CTG CGG GAC TTC CAG CCG GGC CGA CTC TCC CAG CAG ATG GTC ATG GTC AAA TAC CTA 780 F L R D F Q P G R L S Q Q M V M V K Y L 260 GCC ACA CTC GAG CGG CTG GCA CCC CGC TTC GGC ACA GAG CGT GTG CCC GTG TGC CAC CTG 840 A T L E R L A P R F G T E R V P V C H L 280 AGG CTG CTG GCC CAG GCC GAG GGG GAG CCC TGC TAC ATC CGG GAC AGT GGG GTG GCC CCT 900 R L L A Q A E G E P C Y I R D S G V A P 300 ACA GAC CCT GGC CCT GAG TCT GCT GCT GGG CCC CCA ACC CAC GAG GTG CTG GTG ACA GGC 960 T D P G P E S A A G P P T H E V L V T G 320 ACT GGT GGC ATC CAG TGG TGG CCA GTA GAG GAG GAG GTG AAC AAG GAG GAG GGT TCT AGT 1020 T G G I Q W W P V E E E V N K E E G S S 340 GGC AGC AGT GGC AGG AAC CCC CAA GCC AGC CTG TTT GGG AAG AAG GCC AAG GCT CAC AAG 1080 G S S G R N P Q A S L F G K K A K A H K 360 GCA GTC GGC CAG CCG GCA GAC AGG CCG CGG GAG CCA CTG TGG GCC TAC TTC TGT GAC TTC 1140 A V G Q P A D R P R E P L W A Y F C D F 380 CGG GAC ATC ACC CAC GTG GTG CTG AAA GAG CAC TGT GTC AGC ATC CAC CGG CAG GAC AAC 1200 R D I T H V V L K E H C V S I H R Q D N 400 AAG TGC CTG GAG CTG AGC TTG CCT TCC CGG GCT GCG GCG CTG TCC TTC GTG TCG CTG GTG 1260 K C L E L S L P S R A A A L S F V S L V 420 GAC GGC TAT TTC CGC CTG ACG GCC GAC TCC AGC CAC TAC CTG TGC CAC GAG GTG GCT CCC 1320 D G Y F R L T A D S S H Y L C H E V A P 440 CCA CGG CTG GTG ATG AGC ATC CGG GAT GGG ATC CAC GGA CCC CTG CTG GAG CCA TTT GTG 1380 P R L V M S I R D G I H G P L L E P F V 460 CAG GCC AAG CTG CGG CCC GAG GAC GGC CTG TAC CTC ATT CAC TGG AGC ACC AGC CAC CCC 1440 Q A K L R P E D G L Y L I H W S T S H P 480 TAC CGC CTG ATC CTC ACA GTG GCC CAG CGT AGC CAG GCA CCA GAC GGC ATG CAG AGC TTG 1500 Y R L I L T V A Q R S Q A P D G M Q S L 500 CGG CTC CGA AAG TTC CCC ATT GAG CAG CAG GAC GGG GCC TTC GTG CTG GAG GGC TGG GGC 1560 R L R K F P I E Q Q D G A F V L E G W G 520 CGG TCC TTC CCC AGC GTT CGG GAA CTT GGG GCT GCC TTG CAG GGC TGC TTG CTG AGG GCC 1620 R S F P S V R E L G A A L Q G C L L R A 540 GGG GAT GAC TGC TTC TCT CTG CGT CGC TGT TGC CTG CCC CAA CCA GGA GAA ACC TCC AAT 1680 G D D C F S L R R C C L P Q P G E T S N 560 CTC ATC ATC ATG CGG GGG GCT CGG GCC AGC CCC AGG ACA CTC AAC CTC AGC CAG CTC AGC 1740 L I I M R G A R A S P R T L N L S Q L S 580 TTC CAC CGG GTT GAC CAG AAG GAG ATC ACC CAG CTG TCC CAC TTG GGC CAG GGC ACA AGG 1800 F H R V D Q K E I T Q L S H L G Q G T R 600 ACC AAC GTG TAT GAG GGC CGC CTG CGA GTG GAG GGC AGC GGG GAC CCT GAG GAG GGC AAG 1860 T N V Y E G R L R V E G S G D P E E G K 620 ATG GAT GAC GAG GAC CCC CTC GTG CCT GGC AGG GAC CGT GGG CAG GAG CTA CGA GTG GTG 1920 M D D E D P L V P G R D R G Q E L R V V 640 CTC AAA GTG CTG GAC CCT AGT CAC CAT GAC ATC GCC CTG GCC TTC TAC GAG ACA GCC AGC 1980 L K V L D P S H H D I A L A F Y E T A S 660 CTC ATG AGC CAG GTC TCC CAC ACG CAC CTG GCC TTC GTG CAT GGC GTC TGT GTG CGC GGC 2040 L M S Q V S H T H L A F V H G V C V R G 680 CCT GAA AAT ATC ATG GTG ACA GAG TAC GTG GAG CAC GGA CCC CTG GAT GTG TGG CTG CGG 2100 P E N I M V T E Y V E H G P L D V W L R 700 AGG GAG CGG GGC CAT GTG CCC ATG GCT TGG AAG ATG GTG GTG GCC CAG CAG CTG GCC AGC 2160 R E R G H V P M A W K M V V A Q Q L A S 720 GCC CTC AGC TAC CTG GAG AAC AAG AAC CTG GTT CAT GGT AAT GTG TGT GGC CGG AAC ATC 2220 A L S Y L E N K N L V H G N V C G R N I 740 CTG CTG GCC CGG CTG GGG TTG GCA GAG GGC ACC AGC CCC TTC ATC AAG CTG AGT GAT CCT 2280 L L A R L G L A E G T S P F I K L S D P 760 GGC GTG GGC CTG GGC GCC CTC TCC AGG GAG GAG CGG GTG GAG AGG ATC CCC TGG CTG GCC 2340 G V G L G A L S R E E R V E R I P W L A 780 CCC GAA TGC CTA CCA GGT GGG GCC AAC AGC CTA AGC ACC GCC ATG GAC AAG TGG GGG TTT 2400 P E C L P G G A N S L S T A M D K W G F 800 GGC GCC ACC CTC CTG GAG ATC TGC TTT GAC GGA GAG GCC CCT CTG CAG AGC CGC AGT CCC 2460 G A T L L E I C F D G E A P L Q S R S P 820 TCC GAG AAG GAG CAT TTC TAC CAG AGG CAG CAC CGG CTG CCC GAG CCC TCC TGC CCA CAG 2520 S E K E H F Y Q R Q H R L P E P S C P Q 840 CTG GCC ACA CTC ACC AGC CAG TGT CTG ACC TAT GAG CCA ACC CAG AGG CCA TCA TTC CGC 2580 L A T L T S Q C L T Y E P T Q R P S F R 860 ACC ATC CTG CGT GAC CTC ACC CGG CTG CAG CCC CAC AAT CTT GCT GAC GTC TTG ACT GTG 2640 T I L R D L T R L Q P H N L A D V L T V 880 AAC CCG GAC TCA CCG GCG TCG GAC CCT ACG GTT TTC CAC AAG CGC TAT TTG AAA AAG ATC 2700 N P D S P A S D P T V F H K R Y L K K I 900 CGA GAT CTG GGC GAG GGT CAC TTC GGC AAG GTC AGC TTG TAC TGC TAC GAT CCG ACC AAC 2760 R D L G E G H F G K V S L Y C Y D P T N 920 GAC GGC ACT GGC GAG ATG GTG GCG GTG AAA GCC CTC AAG GCA GAC TGC GGC CCC CAG CAC 2820 D G T G E M V A V K A L K A D C G P Q H 940 CGC TCG GGC TGG AAG CAG GAG ATT GAC ATT CTG CGC ACG CTC TAC CAC GAG CAC ATC ATC 2880 R S G W K Q E I D I L R T L Y H E H I I 960 AAG TAC AAG GGC TGC TGC GAG GAC CAA GGC GAG AAG TCG CTG CAG CTG GTC ATG GAG TAC 2940 K Y K G C C E D Q G E K S L Q L V M E Y 980 GTG CCC CTG GGC AGC CTC CGA GAC TAC CTG CCC CGG CAC AGC ATC GGG CTG GCC CAG CTG 3000 V P L G S L R D Y L P R H S I G L A Q L 1000 CTG CTC TTC GCC CAG CAG ATC TGC GAG GGC ATG GCC TAT CTG CAC GCG CAG CAC TAC ATC 3060 L L F A Q Q I C E G M A Y L H A Q H Y I 1020 CAC CGA GAC CTA GCC GCG CGC AAC GTG CTG CTG GAC AAC GAC AGG CTG GTC AAG ATC GGG 3120 H R D L A A R N V L L D N D R L V K I G 1040 GAC TTT GGC CTA GCC AAG GCC GTG CCC GAA GGC CAC GAG TAC TAC CGC GTG CGC GAG GAT 3180 D F G L A K A V P E G H E Y Y R V R E D 1060 GGG GAC AGC CCC GTG TTC TGG TAT GCC CCA GAG TGC CTG AAG GAG TAT AAG TTC TAC TAT 3240 G D S P V F W Y A P E C L K E Y K F Y Y 1080 GCG TCA GAT GTC TGG TCC TTC GGG GTG ACC CTG TAT GAG CTG CTG ACG CAC TGT GAC TCC 3300 A S D V W S F G V T L Y E L L T H C D S 1100 AGC CAG AGC CCC CCC ACG AAA TTC CTT GAG CTC ATA GGC ATT GCT CAG GGT CAG ATG ACA 3360 S Q S P P T K F L E L I G I A Q G Q M T 1120 GTT CTG AGA CTC ACT GAG TTG CTG GAA CGA GGG GAG AGG CTG CCA CGG CCC GAC AAA TGT 3420 V L R L T E L L E R G E R L P R P D K C 1140 CCC TGT GAG GTC TAT CAT CTC ATG AAG AAC TGC TGG GAG ACA GAG GCG TCC TTT CGC CCA 3480 P C E V Y H L M K N C W E T E A S F R P 1160 ACC TTC GAG AAC CTC ATA CCC ATT CTG AAG ACA GTC CAT GAG AAG TAC CAA GGC CAG GCC 3540 T F E N L I P I L K T V H E K Y Q G Q A 1180 CCT TCA GTG TTC AGC GTG TGC TGA 3564 P S V F S V C * 1188