SHANK1 ATG ACC CAC AGC CCC GCG ACA AGC GAG GAC GAG GAA CGC CAC AGT GCC AGC GAG TGT CCC 60 M T H S P A T S E D E E R H S A S E C P 20 GAG GGG GGC TCA GAG TCC GAC AGC TCC CCA GAC GGG CCA GGT CGA GGC CCC CGG GGG ACC 120 E G G S E S D S S P D G P G R G P R G T 40 CGG GGC CAG GGC AGT GGG GCA CCT GGT AGC CTG GCC TCT GTT AGA GGC CTC CAG GGC CGC 180 R G Q G S G A P G S L A S V R G L Q G R 60 TCA ATG TCC GTC CCA GAC GAC GCC CAC TTC AGC ATG ATG GTC TTC AGG ATT GGC ATC CCG 240 S M S V P D D A H F S M M V F R I G I P 80 GAC CTG CAC CAG ACA AAA TGC CTT CGC TTC AAC CCC GAT GCC ACC ATC TGG ACG GCC AAG 300 D L H Q T K C L R F N P D A T I W T A K 100 CAG CAG GTG CTC TGT GCC CTG AGC GAG AGC CTG CAG GAT GTG CTC AAC TAT GGC CTG TTC 360 Q Q V L C A L S E S L Q D V L N Y G L F 120 CAA CCG GCC ACC TCC GGC CGC GAT GCC AAC TTC CTG GAG GAG GAG AGG CTG CTG CGG GAG 420 Q P A T S G R D A N F L E E E R L L R E 140 TAC CCC CAG TCC TTT GAG AAG GGG GTC CCC TAC CTG GAG TTC CGA TAC AAG ACC CGA GTT 480 Y P Q S F E K G V P Y L E F R Y K T R V 160 TAC AAA CAG ACC AAC CTG GAT GAG AAG CAG CTG GCC AAG TTG CAC ACG AAG ACG GGG TTG 540 Y K Q T N L D E K Q L A K L H T K T G L 180 AAG AAG TTC CTG GAG TAT GTG CAG CTC GGG ACA TCT GAC AAG GTG GCG CGG CTG CTG GAC 600 K K F L E Y V Q L G T S D K V A R L L D 200 AAG GGG CTG GAC CCC AAT TAC CAT GAC TCG GAT TCG GGA GAG ACC CCC TTG ACA CTG GCG 660 K G L D P N Y H D S D S G E T P L T L A 220 GCC CAG ACC GAA GGC TCT GTA GAG GTG ATT CGA ACC CTG TGC CTG GGC GGG GCC CAC ATT 720 A Q T E G S V E V I R T L C L G G A H I 240 GAC TTC CGG GCC CGG GAT GGC ATG ACC GCA CTG CAT AAG GCC GCA TGC GCC CGA CAC TGC 780 D F R A R D G M T A L H K A A C A R H C 260 CTG GCA CTC ACG GCG CTC CTG GAC CTT GGG GGT TCC CCC AAC TAC AAG GAC CGT CGG GGG 840 L A L T A L L D L G G S P N Y K D R R G 280 CTG ACC CCT CTG TTC CAC ACG GCC ATG GTG GGT GGT GAC CCC CGA TGC TGC GAG CTG CTC 900 L T P L F H T A M V G G D P R C C E L L 300 CTG TTC AAC AGG GCC CAG CTG GGC ATA GCT GAT GAG AAC GGC TGG CAG GAA ATC CAC CAG 960 L F N R A Q L G I A D E N G W Q E I H Q 320 GCC TGC CAG CGG GGT CAC TCT CAG CAC CTG GAG CAT CTG CTT TTC TAC GGG GCT GAG CCT 1020 A C Q R G H S Q H L E H L L F Y G A E P 340 GGA GCC CAG AAC GCC TCG GGG AAC ACG GCT CTG CAC ATC TGC GCC CTC TAC AAC AAG GAG 1080 G A Q N A S G N T A L H I C A L Y N K E 360 ACC TGT GCC AGG ATC CTC CTG TAT CGA GGT GCC GAC AAG GAT GTG AAG AAC AAC AAC GGA 1140 T C A R I L L Y R G A D K D V K N N N G 380 CAG ACC CCC TTC CAG GTG GCA GTG ATT GCT GGG AAT TTT GAG CTG GGG GAG CTG ATC CGA 1200 Q T P F Q V A V I A G N F E L G E L I R 400 AAC CAC CGA GAA CAG GAT GTG GTG CCC TTC CAG GAG TCC CCC AAG TAC GCG GCC CGG CGA 1260 N H R E Q D V V P F Q E S P K Y A A R R 420 CGG GGG CCC CCA GGC ACA GGG CTG ACG GTG CCC CCG GCG CTG CTG CGG GCC AAC AGT GAC 1320 R G P P G T G L T V P P A L L R A N S D 440 ACC AGC ATG GCG CTG CCC GAC TGG ATG GTG TTC TCC GCC CCG GGG GCC GCG TCC TCT GGG 1380 T S M A L P D W M V F S A P G A A S S G 460 GCC CCT GGC CCT ACC TCA GGG TCC CAG GGC CAG TCG CAG CCC TCG GCC CCC ACC ACC AAG 1440 A P G P T S G S Q G Q S Q P S A P T T K 480 CTC AGC AGC GGG ACC CTC CGA AGT GCC AGC AGC CCC CGG GGT GCC AGG GCC CGC TCT CCA 1500 L S S G T L R S A S S P R G A R A R S P 500 TCC CGA GGG AGG CAC CCT GAG GAC GCC AAG AGG CAG CCC CGA GGC CGG CCC AGC TCC AGC 1560 S R G R H P E D A K R Q P R G R P S S S 520 GGG ACA CCC CGG GAA GGG CCA GCC GGG GGC ACG GGG GGC TCA GGG GGC CCC GGG GGC TCC 1620 G T P R E G P A G G T G G S G G P G G S 540 CTG GGC AGC CGC GGG AGG CGG AGG AAG CTC TAC TCA GCG GTA CCC GGA CGC TCC TTC ATG 1680 L G S R G R R R K L Y S A V P G R S F M 560 GCT GTG AAG TCC TAC CAG GCC CAA GCC GAG GGG GAG ATC TCC CTG AGC AAG GGC GAG AAG 1740 A V K S Y Q A Q A E G E I S L S K G E K 580 ATC AAA GTA CTT AGC ATC GGG GAA GGA GGC TTC TGG GAA GGC CAG GTC AAA GGT CGT GTT 1800 I K V L S I G E G G F W E G Q V K G R V 600 GGC TGG TTC CCC TCT GAC TGC CTG GAA GAA GTG GCG AAT CGC TCT CAG GAG AGC AAG CAA 1860 G W F P S D C L E E V A N R S Q E S K Q 620 GAA AGC CGC AGT GAC AAG GCA AAG AGA CTC TTC CGG CAT TAT ACC GTG GGC TCC TAC GAC 1920 E S R S D K A K R L F R H Y T V G S Y D 640 AGC TTT GAT GCC CCA AGC TTA ATG GAT GGG ATT GGC CCA GGG AGC GAT TAC ATC ATT AAG 1980 S F D A P S L M D G I G P G S D Y I I K 660 GAG AAG ACA GTC TTG CTG CAG AAG AAG GAC AGT GAG GGG TTT GGG TTC GTG CTC CGG GGG 2040 E K T V L L Q K K D S E G F G F V L R G 680 GCC AAG GCG CAG ACC CCC ATC GAG GAG TTC ACC CCC ACC CCG GCC TTC CCG GCG CTG CAG 2100 A K A Q T P I E E F T P T P A F P A L Q 700 TAC CTG GAG TCG GTG GAC GAG GGT GGC GTG GCA TGG CGA GCT GGA CTG CGA ATG GGA GAC 2160 Y L E S V D E G G V A W R A G L R M G D 720 TTC CTC ATC GAG GTG AAC GGG CAG AAT GTG GTG AAG GTC GGC CAC CGA CAG GTG GTG AAC 2220 F L I E V N G Q N V V K V G H R Q V V N 740 ATG ATC CGC CAA GGG GGC AAC ACG CTG ATG GTG AAG GTG GTG ATG GTC ACC AGG CAC CCG 2280 M I R Q G G N T L M V K V V M V T R H P 760 GAC ATG GAT GAG GCA GTG CAC AAG AAA GCA CCC CAG CAG GCC AAG CGG CTG CCG CCC CCA 2340 D M D E A V H K K A P Q Q A K R L P P P 780 ACC ATC TCC CTG CGT TCC AAA TCT ATG ACC TCA GAG CTG GAG GAG ATG GAG TAC GAG CAG 2400 T I S L R S K S M T S E L E E M E Y E Q 800 CAG CCG GCG CCG GTG CCC AGC ATG GAG AAA AAG CGG ACC GTG TAT CAG ATG GCT CTC AAC 2460 Q P A P V P S M E K K R T V Y Q M A L N 820 AAA CTG GAC GAA ATC CTG GCC GCA GCT CAA CAG ACC ATC AGT GCA AGC GAA AGC CCT GGT 2520 K L D E I L A A A Q Q T I S A S E S P G 840 CCC GGT GGC CTC GCG TCC CTG GGC AAA CAC CGA CCC AAA GGT TTC TTT GCC ACT GAG TCG 2580 P G G L A S L G K H R P K G F F A T E S 860 AGC TTC GAT CCC CAC CAC CGT GCC CAG CCA AGT TAC GAG CGT CCT TCT TTC CTG CCT CCA 2640 S F D P H H R A Q P S Y E R P S F L P P 880 GGA CCT GGG TTG ATG CTC CGG CAA AAA TCT ATC GGT GCG GCA GAA GAT GAC AGA CCT TAC 2700 G P G L M L R Q K S I G A A E D D R P Y 900 CTA GCA CCC CCA GCC ATG AAA TTC AGC CGC AGC CTG TCT GTG CCT GGT TCG GAG GAC ATT 2760 L A P P A M K F S R S L S V P G S E D I 920 CCC CCG CCA CCC ACC ACG TCC CCA CCG GAG CCT CCC TAC AGC ACA CCT CCA GTC CCC TCC 2820 P P P P T T S P P E P P Y S T P P V P S 940 TCC TCA GGG CGC CTC ACC CCC TCC CCT CGG GGA GGG CCC TTC AAC CCT GGC TCT GGT GGC 2880 S S G R L T P S P R G G P F N P G S G G 960 CCC CTC CCC GCC TCC TCC CCT GCA TCC TTT GAC GGG CCC TCC CCT CCC GAC ACT CGC GTG 2940 P L P A S S P A S F D G P S P P D T R V 980 GGG AGC CGC GAG AAG AGC CTG TAC CAC AGT GGG CCC CTG CCC CCG GCC CAC CAC CAC CCG 3000 G S R E K S L Y H S G P L P P A H H H P 1000 CCC CAC CAC CAC CAC CAC CAC GCC CCG CCC CCT CAG CCC CAC CAC CAC CAC GCC CAC CCC 3060 P H H H H H H A P P P Q P H H H H A H P 1020 CCT CAT CCT CCC GAG ATG GAG ACA GGC GGC TCT CCC GAC GAC CCT CCA CCC CGC CTG GCT 3120 P H P P E M E T G G S P D D P P P R L A 1040 CTG GGG CCC CAG CCC AGC CTG CGA GGC TGG AGG GGC GGC GGG CCC AGC CCG ACC CCG GGG 3180 L G P Q P S L R G W R G G G P S P T P G 1060 GCC CCG TCC CCA TCG CAC CAC GGC AGC GCG GGC GGG GGC GGC GGC TCC TCC CAG GGC CCG 3240 A P S P S H H G S A G G G G G S S Q G P 1080 GCT CTA CGC TAT TTC CAG CTG CCC CCG CGG GCG GCC AGC GCA GCC ATG TAC GTG CCC GCC 3300 A L R Y F Q L P P R A A S A A M Y V P A 1100 CGC TCG GGC CGC GGC CGC AAG GGC CCG CTG GTC AAG CAG ACC AAG GTG GAA GGC GAG CCC 3360 R S G R G R K G P L V K Q T K V E G E P 1120 CAG AAG GGC GGC GGC CTC CCG CCC GCG CCG TCG CCC ACG TCC CCG GCC TCC CCG CAG CCG 3420 Q K G G G L P P A P S P T S P A S P Q P 1140 CCG CCC GCC GTG GCC GCG CCC TCG GAG AAG AAC TCC ATC CCC ATC CCC ACC ATC ATC ATC 3480 P P A V A A P S E K N S I P I P T I I I 1160 AAG GCC CCG TCC ACC AGT AGC AGC GGC CGC AGC AGC CAG GGC AGC AGC ACC GAG GCG GAG 3540 K A P S T S S S G R S S Q G S S T E A E 1180 CCC CCC ACC CAG CCG GAG CCC ACG GGA GGC GGC GGC GGC GGC GGC TCC TCG CCC AGC CCC 3600 P P T Q P E P T G G G G G G G S S P S P 1200 GCC CCG GCC ATG TCA CCC GTG CCC CCG TCC CCC TCG CCC GTG CCC ACC CCC GCC TCG CCC 3660 A P A M S P V P P S P S P V P T P A S P 1220 AGC GGC CCG GCC ACG CTG GAC TTC ACG AGC CAG TTC GGG GCC GCC CTG GTG GGG GCG GCC 3720 S G P A T L D F T S Q F G A A L V G A A 1240 CGG AGG GAG GGG GGC TGG CAG AAT GAG GCG CGC CGG CGC TCC ACG CTG TTC CTG TCC ACC 3780 R R E G G W Q N E A R R R S T L F L S T 1260 GAC GCG GGG GAC GAG GAC GGC GGG GAC GGC GGG CTG GGC ACA GGG GCG GCC CCG GGC CCG 3840 D A G D E D G G D G G L G T G A A P G P 1280 CGG CTG CGC CAC TCC AAA TCC ATC GAC GAG GGC ATG TTC TCC GCC GAG CCC TAC CTC CGA 3900 R L R H S K S I D E G M F S A E P Y L R 1300 CTG GAG TCT GCG GGC AGC GGC GCG GGC TAC GGC GGC TAC GGG GCC GGT AGC CGA GCC TAC 3960 L E S A G S G A G Y G G Y G A G S R A Y 1320 GGG GGT GGC GGG GGC AGC AGC GCC TTC ACC AGC TTC CTG CCC CCG CGA CCC CTG GTG CAC 4020 G G G G G S S A F T S F L P P R P L V H 1340 CCG CTG ACC GGC AAG GCC CTG GAT CCC GCC TCC CCG CTG GGG CTG GCC CTG GCC GCC CGC 4080 P L T G K A L D P A S P L G L A L A A R 1360 GAG CGA GCG CTG AAG GAG TCC TCG GAG GGC GGC GGG GCC CCC CAG CCG CCT CCC AGG CCC 4140 E R A L K E S S E G G G A P Q P P P R P 1380 CCA TCG CCC CGC TAC GAG GCC CCG CCG CCC ACC CCG CAC CAC CAC TCG CCC CAC GCC CAC 4200 P S P R Y E A P P P T P H H H S P H A H 1400 CAC GAG CCA GTG CTG CGT CTC TGG GGG GCC TCC CCG CCG GAC CCT GCG CGC CGG GAG CTG 4260 H E P V L R L W G A S P P D P A R R E L 1420 GGG TAC AGG GCC GGG CTG GGC AGC CAG GAG AAG TCC CTT CCC GCC AGC CCG CCC GCC GCC 4320 G Y R A G L G S Q E K S L P A S P P A A 1440 CGG CGT TCC CTG CTA CAC CGC CTG CCG CCC ACC GCT CCC GGG GTG GGG CCC CTC CTG CTG 4380 R R S L L H R L P P T A P G V G P L L L 1460 CAG CTG GGG ACG GAG CCC CCG GCC CCG CAC CCC GGA GTA AGC AAG CCC TGG AGG TCC GCA 4440 Q L G T E P P A P H P G V S K P W R S A 1480 GCC CCC GAA GAA CCC GAG CGG CTG CCG CTG CAC GTG CGG TTC CTT GAA AAC TGC CAG CCC 4500 A P E E P E R L P L H V R F L E N C Q P 1500 CGG GCC CCT GTG ACG AGC GGA AGG GGT CCC CCC TCG GAG GAC GGG CCG GGG GTC CCG CCG 4560 R A P V T S G R G P P S E D G P G V P P 1520 CCC AGC CCA CGC CGG TCC GTG CCC CCC TCC CCG ACC TCC CCG AGG GCC AGC GAA GAG AAC 4620 P S P R R S V P P S P T S P R A S E E N 1540 GGG CTG CCC CTG CTG GTC CTG CCG CCT CCC GCC CCC TCG GTG GAT GTG GAA GAT GGC GAA 4680 G L P L L V L P P P A P S V D V E D G E 1560 TTC CTT TTC GTG GAA CCG CTG CCT CCG CCT CTG GAA TTC TCC AAC AGC TTC GAA AAG CCA 4740 F L F V E P L P P P L E F S N S F E K P 1580 GAG TCG CCC CTC ACG CCT GGG CCT CCC CAC CCG CTG CCC GAC ACA CCT GCC CCT GCC ACC 4800 E S P L T P G P P H P L P D T P A P A T 1600 CCG TTA CCC CCT GTG CCA CCC CCG GCT GTG GCC GCA GCC CCT CCC ACC CTG GAC TCC ACC 4860 P L P P V P P P A V A A A P P T L D S T 1620 GCA TCC AGC CTG ACA TCC TAT GAC AGC GAG GTG GCC ACC CTG ACC CAG GGG GCC TCC GCC 4920 A S S L T S Y D S E V A T L T Q G A S A 1640 GCT CCT GGG GAC CCC CAT CCA CCA GGC CCG CCT GCC CCA GCA GCA CCG GCT CCC GCT GCC 4980 A P G D P H P P G P P A P A A P A P A A 1660 CCA CAG CCT GGC CCG GAC CCT CCG CCT GGC ACG GAT TCT GGC ATC GAG GAG GTG GAC AGT 5040 P Q P G P D P P P G T D S G I E E V D S 1680 CGG AGC AGC AGT GAC CAC CCA CTG GAG ACC ATC AGC AGC GCC TCC ACG CTG AGC AGC CTA 5100 R S S S D H P L E T I S S A S T L S S L 1700 TCT GCC GAA GGT GGT GGC AGC GCA GGG GGT GGG GGC GGG GCT GGG GCC GGT GTG GCC AGT 5160 S A E G G G S A G G G G G A G A G V A S 1720 GGG CCG GAG CTT CTG GAC ACC TAT GTG GCC TAC CTG GAC GGC CAG GCC TTT GGG GGC AGC 5220 G P E L L D T Y V A Y L D G Q A F G G S 1740 AGT ACT CCC GGC CCG CCA TAC CCT CCT CAG CTC ATG ACT CCC TCT AAG CTC CGG GGC CGG 5280 S T P G P P Y P P Q L M T P S K L R G R 1760 GCG CTA GGA GCC AGC GGA GGC CTG CGG CCT GGC CCC AGC GGG GGA CTC CGA GAC CCT GTT 5340 A L G A S G G L R P G P S G G L R D P V 1780 ACC CCC ACC AGC CCC ACC GTC TCG GTG ACA GGG GCT GGA ACC GAT GGG CTG CTG GCC CTG 5400 T P T S P T V S V T G A G T D G L L A L 1800 CGT GCT TGT TCA GGA CCC CCC ACG GCA GGC GTG GCG GGG GGT CCG GTG GCT GTA GAG CCA 5460 R A C S G P P T A G V A G G P V A V E P 1820 GAA GTC CCA CCG GTG CCC TTG CCG ACG GCC TCC TCT CTG CCC CGG AAG CTG CTG CCC TGG 5520 E V P P V P L P T A S S L P R K L L P W 1840 GAG GAG GGC CCG GGC CCA CCG CCA CCA CCT CTG CCC GGG CCC TTG GCC CAG CCT CAG GCC 5580 E E G P G P P P P P L P G P L A Q P Q A 1860 TCA GCC TTG GCC ACA GTA AAA GCC AGC ATC ATC AGT GAA CTC AGC TCC AAG CTT CAG CAG 5640 S A L A T V K A S I I S E L S S K L Q Q 1880 TTT GGG GGC TCC TCG GCA GCT GGC GGC GCT CTG CCC TGG GCC CGA GGA GGC AGT GGG GGA 5700 F G G S S A A G G A L P W A R G G S G G 1900 GGC GGA GAC AGC CAC CAC GGG GGA GCC AGC TAT GTC CCC GAG AGG ACC TCC TCC CTG CAG 5760 G G D S H H G G A S Y V P E R T S S L Q 1920 CGG CAG AGA CTC TCC GAC GAC TCC CAG TCC TCA CTC CTC TCC AAG CCT GTC AGC AGC CTG 5820 R Q R L S D D S Q S S L L S K P V S S L 1940 TTT CAG AAC TGG CCC AAA CCA CCT CTG CCG CCA CTC CCC ACC GGA ACA GGG GTC TCC CCT 5880 F Q N W P K P P L P P L P T G T G V S P 1960 ACA GCC GCT GCG GCC CCA GGG GCC ACC TCA CCC TCA GCC TCC TCC TCC TCC ACG TCC ACC 5940 T A A A A P G A T S P S A S S S S T S T 1980 CGC CAC CTC CAG GGC GTG GAG TTC GAG ATG CGG CCC CCT CTG CTC CGC CGG GCC CCC AGC 6000 R H L Q G V E F E M R P P L L R R A P S 2000 CCC TCG CTG CTG CCC GCC TCG GAG CAC AAG GTC AGC CCT GCG CCC AGG CCC TCG TCC CTG 6060 P S L L P A S E H K V S P A P R P S S L 2020 CCC ATC CTG CCT TCC GGA CCC CTC TAC CCA GGC CTC TTT GAC ATC CGT GGC TCC CCA ACT 6120 P I L P S G P L Y P G L F D I R G S P T 2040 GGA GGG GCA GGA GGC TCG GCT GAC CCC TTC GCC CCA GTC TTT GTG CCG CCA CAC CCG GGG 6180 G G A G G S A D P F A P V F V P P H P G 2060 ATA TCC GGG GGG CTC GGG GGA GCC TTG TCA GGG GCC TCG CGC TCC CTC TCA CCG ACC CGC 6240 I S G G L G G A L S G A S R S L S P T R 2080 CTG CTC TCG CTG CCC CCG GAC AAG CCG TTT GGC GCT AAA CCT CTG GGG TTC TGG ACC AAG 6300 L L S L P P D K P F G A K P L G F W T K 2100 TTC GAC GTG GCT GAT TGG CTG GAG TGG CTG GGT TTG GCG GAG CAC CGA GCC CAG TTC CTG 6360 F D V A D W L E W L G L A E H R A Q F L 2120 GAC CAC GAG ATC GAT GGC TCC CAC CTG CCC GCC TTG ACC AAG GAG GAC TAC GTC GAT CTA 6420 D H E I D G S H L P A L T K E D Y V D L 2140 GGT GTG ACC AGG GTG GGC CAC CGC ATG AAC ATC GAC CGG GCT CTC AAA TTC TTC CTG GAG 6480 G V T R V G H R M N I D R A L K F F L E 2160 AGG TGA 6486 R * 2162