LRRK1 ATG GCT GGC ATG TCG CAA AGA CCC CCC AGC ATG TAC TGG TGT GTG GGG CCG GAG GAG TCA 60 M A G M S Q R P P S M Y W C V G P E E S 20 GCT GTG TGT CCA GAA CGT GCC ATG GAG ACG CTT AAC GGT GCC GGG GAC ACG GGC GGC AAG 120 A V C P E R A M E T L N G A G D T G G K 40 CCG TCC ACG CGG GGC GGT GAC CCT GCA GCG CGG TCC CGC AGG ACG GAA GGC ATC CGC GCC 180 P S T R G G D P A A R S R R T E G I R A 60 GCG TAC AGG CGG GGA GAC CGC GGC GGC GCC CGG GAC CTG CTG GAG GAG GCC TGC GAC CAG 240 A Y R R G D R G G A R D L L E E A C D Q 80 TGC GCG TCC CAG CTG GAA AAG GGC CAG CTT CTG AGC ATC CCG GCA GCC TAT GGG GAT CTG 300 C A S Q L E K G Q L L S I P A A Y G D L 100 GAG ATG GTC CGC TAC CTA CTC AGC AAG AGA CTG GTG GAG CTG CCC ACC GAG CCC ACG GAT 360 E M V R Y L L S K R L V E L P T E P T D 120 GAC AAC CCA GCC GTG GTG GCA GCG TAT TTT GGA CAC ACG GCA GTT GTG CAG GAA TTG CTT 420 D N P A V V A A Y F G H T A V V Q E L L 140 GAG TCC TTA CCA GGT CCC TGC AGT CCC CAG CGG CTT CTG AAC TGG ATG CTG GCC TTG GCT 480 E S L P G P C S P Q R L L N W M L A L A 160 TGC CAG CGA GGG CAC CTG GGG GTT GTG AAG CTC CTG GTC CTG ACG CAC GGG GCT GAC CCG 540 C Q R G H L G V V K L L V L T H G A D P 180 GAG AGC TAC GCT GTC AGG AAG AAT GAG TTC CCT GTC ATC GTG CGC TTG CCC CTG TAT GCG 600 E S Y A V R K N E F P V I V R L P L Y A 200 GCC ATC AAG TCA GGG AAT GAA GAC ATT GCA ATA TTC CTG CTT CGG CAT GGG GCC TAT TTC 660 A I K S G N E D I A I F L L R H G A Y F 220 TGT TCC TAC ATC TTG CTG GAT AGT CCT GAC CCC AGC AAA CAT CTG CTG AGA AAG TAC TTC 720 C S Y I L L D S P D P S K H L L R K Y F 240 ATT GAA GCC AGT CCC TTG CCC AGC AGT TAT CCG GGA AAA ACA GCT CTC CGT GTG AAA TGG 780 I E A S P L P S S Y P G K T A L R V K W 260 TCC CAT CTC AGA CTG CCC TGG GTA GAC CTA GAC TGG CTC ATA GAC ATC TCC TGC CAG ATC 840 S H L R L P W V D L D W L I D I S C Q I 280 ACG GAG CTC GAC CTT TCT GCC AAC TGC CTG GCG ACC CTC CCC TCG GTT ATC CCC TGG GGC 900 T E L D L S A N C L A T L P S V I P W G 300 CTC ATC AAT CTC CGG AAG CTG AAC CTC TCC GAC AAC CAC CTG GGG GAG CTG CCT GGC GTG 960 L I N L R K L N L S D N H L G E L P G V 320 CAG TCA TCG GAC GAA ATC ATC TGT TCC AGG CTA CTT GAA ATT GAC ATT TCC AGC AAC AAG 1020 Q S S D E I I C S R L L E I D I S S N K 340 TTG TCC CAC CTC CCT CCT GGA TTC TTG CAC CTC TCA AAA CTT CAA AAA CTG ACA GCT TCA 1080 L S H L P P G F L H L S K L Q K L T A S 360 AAA AAT TGT TTA GAA AAA TTG TTC GAA GAA GAA AAT GCC ACT AAC TGG ATA GGT TTA CGG 1140 K N C L E K L F E E E N A T N W I G L R 380 AAG CTA CAG GAA CTT GAT ATA TCT GAC AAT AAA TTG ACA GAA CTC CCT GCC CTG TTC CTT 1200 K L Q E L D I S D N K L T E L P A L F L 400 CAC TCT TTC AAG TCC CTC AAT TCT CTG AAT GTC TCC AGA AAC AAC CTG AAG GTG TTT CCA 1260 H S F K S L N S L N V S R N N L K V F P 420 GAT CCC TGG GCC TGC CCT TTG AAA TGT TGT AAA GCT TCC AGA AAT GCC CTG GAA TGT CTG 1320 D P W A C P L K C C K A S R N A L E C L 440 CCA GAC AAA ATG GCT GTC TTT TGG AAA AAT CAC CTG AAG GAT GTG GAT TTC TCA GAA AAC 1380 P D K M A V F W K N H L K D V D F S E N 460 GCA CTC AAA GAA GTT CCC CTG GGA CTT TTC CAG CTT GAT GCC CTC ATG TTC TTG AGG TTA 1440 A L K E V P L G L F Q L D A L M F L R L 480 CAG GGG AAC CAG CTG GCG GCA CTT CCA CCT CAA GAG AAG TGG ACC TGC AGG CAG CTC AAA 1500 Q G N Q L A A L P P Q E K W T C R Q L K 500 ACC CTG GAT CTC TCC AGA AAC CAA CTT GGC AAA AAT GAA GAT GGA CTG AAA ACG AAG CGT 1560 T L D L S R N Q L G K N E D G L K T K R 520 ATT GCC TTT TTC ACC ACC AGA GGT CGC CAG CGC TCC GGG ACT GAG GCA GCA AGT GTG CTG 1620 I A F F T T R G R Q R S G T E A A S V L 540 GAA TTT CCG GCC TTC CTA AGT GAG TCT TTG GAA GTC CTT TGC CTG AAC GAC AAC CAC CTC 1680 E F P A F L S E S L E V L C L N D N H L 560 GAC ACA GTC CCT CCC TCG GTT TGC CTA CTG AAG AGC TTA TCA GAG CTC TAC TTG GGA AAC 1740 D T V P P S V C L L K S L S E L Y L G N 580 AAC CCT GGC CTC CGG GAG CTC CCT CCT GAG CTG GGG CAG CTG GGC AAC CTC TGG CAG CTG 1800 N P G L R E L P P E L G Q L G N L W Q L 600 GAC ACT GAA GAC CTG ACC ATC AGC AAT GTG CCT GCA GAA ATC CAA AAA GAA GGC CCC AAA 1860 D T E D L T I S N V P A E I Q K E G P K 620 GCA ATG CTG TCT TAC CTG CGT GCT CAG CTG CGG AAA GCG GAA AAG TGC AAG CTG ATG AAG 1920 A M L S Y L R A Q L R K A E K C K L M K 640 ATG ATC ATC GTG GGT CCC CCG CGC CAG GGC AAG TCC ACC CTC CTG GAG ATC TTA CAG ACG 1980 M I I V G P P R Q G K S T L L E I L Q T 660 GGG AGG GCC CCC CAG GTG GTG CAT GGA GAG GCC ACC ATC AGG ACC ACC AAG TGG GAG CTC 2040 G R A P Q V V H G E A T I R T T K W E L 680 CAG AGG CCG GCT GGC TCG AGA GCC AAG GTT GAG TCC GTG GAG TTC AAC GTC TGG GAC ATC 2100 Q R P A G S R A K V E S V E F N V W D I 700 GGG GGA CCG GCC AGC ATG GCC ACT GTC AAC CAG TGC TTC TTC ACG GAC AAG GCC CTG TAC 2160 G G P A S M A T V N Q C F F T D K A L Y 720 GTG GTG GTC TGG AAC CTG GCG CTG GGG GAG GAG GCC GTG GCC AAC CTC CAG TTC TGG CTG 2220 V V V W N L A L G E E A V A N L Q F W L 740 CTC AAC ATC GAG GCC AAG GCC CCA AAC GCC GTG GTG CTG GTG GTC GGG ACG CAC CTG GAT 2280 L N I E A K A P N A V V L V V G T H L D 760 TTA ATT GAA GCC AAG TTC CGT GTG GAA AGG ATT GCA ACG CTG CGT GCC TAT GTG CTG GCA 2340 L I E A K F R V E R I A T L R A Y V L A 780 CTC TGC CGC TCC CCC TCC GGC TCC AGG GCC ACA GGC TTC CCA GAC ATC ACC TTC AAA CAC 2400 L C R S P S G S R A T G F P D I T F K H 800 TTA CAT GAG ATT TCC TGC AAG AGC CTG GAA GGT CAG GAA GGG CTG CGA CAG CTG ATT TTC 2460 L H E I S C K S L E G Q E G L R Q L I F 820 CAC GTC ACG TGC AGC ATG AAG GAC GTG GGC AGC ACC ATC GGC TGC CAG CGA CTG GCA GGG 2520 H V T C S M K D V G S T I G C Q R L A G 840 CGG CTG ATC CCC AGG AGC TAC CTG AGC CTG CAG GAG GCC GTG CTG GCA GAG CAG CAG CGC 2580 R L I P R S Y L S L Q E A V L A E Q Q R 860 CGC AGC CGG GAC GAC GAC GTG CAG TAC CTG ACG GAC AGG CAG CTG GAG CAG CTG GTG GAG 2640 R S R D D D V Q Y L T D R Q L E Q L V E 880 CAG ACG CCC GAC AAC GAC ATC AAG GAC TAC GAG GAC CTG CAG TCA GCC ATC AGC TTC CTC 2700 Q T P D N D I K D Y E D L Q S A I S F L 900 ATA GAA ACC GGC ACC CTG CTC CAT TTC CCG GAC ACC AGC CAC GGC CTG AGG AAC CTC TAC 2760 I E T G T L L H F P D T S H G L R N L Y 920 TTC CTC GAC CCT ATT TGG CTC TCC GAA TGT CTG CAG AGG ATC TTT AAT ATT AAG GGC TCT 2820 F L D P I W L S E C L Q R I F N I K G S 940 CGG TCA GTG GCC AAG AAT GGG GTG ATC AGA GCA GAA GAC CTC AGG ATG CTG CTG GTG GGG 2880 R S V A K N G V I R A E D L R M L L V G 960 ACT GGC TTC ACG CAG CAG ACG GAA GAG CAG TAC TTC CAG TTC CTG GCC AAG TTT GAG ATC 2940 T G F T Q Q T E E Q Y F Q F L A K F E I 980 GCC CTG CCC GTC GCC AAT GAC AGC TAC CTC CTG CCC CAT CTC CTT CCA TCT AAA CCT GGC 3000 A L P V A N D S Y L L P H L L P S K P G 1000 CTG GAC ACC CAC GGT ATG CGG CAC CCC ACA GCC AAC ACC ATT CAG AGG GTA TTT AAG ATG 3060 L D T H G M R H P T A N T I Q R V F K M 1020 AGC TTC GTT CCC GTT GGC TTC TGG CAA AGG TTT ATA GCA CGG ATG CTG ATC AGC CTG GCG 3120 S F V P V G F W Q R F I A R M L I S L A 1040 GAG ATG GAC CTG CAG CTT TTT GAA AAC AAG AAG AAT ACT AAA AGC AGG AAC AGG AAA GTC 3180 E M D L Q L F E N K K N T K S R N R K V 1060 ACC ATT TAC AGT TTT ACA GGA AAC CAG AGA AAT CGC TGT AGC ACA TTC AGA GTG AAA AGA 3240 T I Y S F T G N Q R N R C S T F R V K R 1080 AAT CAG ACC ATC TAT TGG CAG GAA GGG CTC CTG GTC ACT TTT GAT GGG GGC TAC CTC AGT 3300 N Q T I Y W Q E G L L V T F D G G Y L S 1100 GTG GAA TCT TCC GAC GTG AAC TGG AAA AAG AAG AAA AGC GGA GGA ATG AAA ATT GTT TGC 3360 V E S S D V N W K K K K S G G M K I V C 1120 CAA TCA GAA GTG AGG GAC TTC TCA GCC ATG GCT TTC ATC ACG GAC CAC GTC AAT TCC TTG 3420 Q S E V R D F S A M A F I T D H V N S L 1140 ATT GAT CAG TGG TTT CCC GCC CTG ACA GCC ACA GAG AGC GAC GGG ACG CCA CTC ATG GAG 3480 I D Q W F P A L T A T E S D G T P L M E 1160 CAG TAC GTG CCC TGC CCG GTC TGC GAG ACA GCC TGG GCC CAG CAC ACG GAC CCC AGT GAG 3540 Q Y V P C P V C E T A W A Q H T D P S E 1180 AAA TCA GAG GAT GTG CAG TAC TTC GAC ATG GAA GAC TGT GTC CTG ACG GCC ATC GAG CGG 3600 K S E D V Q Y F D M E D C V L T A I E R 1200 GAC TTC ATC TCC TGC CCC AGA CAC CCG GAC CTC CCC GTG CCG CTG CAG GAG CTG GTC CCT 3660 D F I S C P R H P D L P V P L Q E L V P 1220 GAA CTG TTC ATG ACC GAC TTC CCG GCC AGG CTC TTC CTG GAG AAC AGC AAG CTG GAG CAC 3720 E L F M T D F P A R L F L E N S K L E H 1240 AGC GAG GAC GAG GGC AGC GTC CTG GGC CAG GGC GGC AGT GGC ACC GTC ATC TAC CGG GCC 3780 S E D E G S V L G Q G G S G T V I Y R A 1260 CGG TAC CAG GGC CAG CCT GTG GCC GTC AAG CGC TTC CAC ATC AAA AAA TTC AAG AAC TTT 3840 R Y Q G Q P V A V K R F H I K K F K N F 1280 GCT AAC GTA CCG GCA GAC ACC ATG CTG AGG CAC CTG CGG GCC ACC GAT GCC ATG AAG AAC 3900 A N V P A D T M L R H L R A T D A M K N 1300 TTC TCC GAG TTC CGG CAG GAG GCC AGC ATG CTG CAC GCG CTG CAG CAC CCC TGC ATC GTG 3960 F S E F R Q E A S M L H A L Q H P C I V 1320 GCG CTC ATC GGC ATC AGC ATC CAC CCG CTC TGC TTC GCC CTG GAG CTC GCG CCG CTC AGC 4020 A L I G I S I H P L C F A L E L A P L S 1340 AGC CTC AAC ACC GTG CTG TCC GAG AAC GCC AGA GAT TCT TCC TTT ATA CCC CTG GGA CAC 4080 S L N T V L S E N A R D S S F I P L G H 1360 ATG CTC ACC CAA AAA ATA GCC TAC CAG ATC GCC TCG GGC CTG GCC TAC CTG CAC AAG AAA 4140 M L T Q K I A Y Q I A S G L A Y L H K K 1380 AAC ATC ATC TTC TGT GAC CTG AAG TCG GAC AAC ATT CTG GTG TGG TCC CTT GAC GTC AAG 4200 N I I F C D L K S D N I L V W S L D V K 1400 GAG CAC ATC AAC ATC AAG CTA TCT GAC TAC GGG ATT TCG AGG CAG TCA TTC CAT GAG GGC 4260 E H I N I K L S D Y G I S R Q S F H E G 1420 GCC CTA GGC GTG GAG GGC ACT CCT GGC TAC CAG GCC CCA GAG ATC AGG CCT CGC ATT GTA 4320 A L G V E G T P G Y Q A P E I R P R I V 1440 TAT GAT GAG AAG GTA GAT ATG TTC TCC TAT GGA ATG GTG CTC TAC GAG TTG CTG TCA GGA 4380 Y D E K V D M F S Y G M V L Y E L L S G 1460 CAG CGC CCT GCA CTG GGC CAC CAC CAG CTC CAG ATT GCC AAG AAG CTG TCC AAG GGC ATC 4440 Q R P A L G H H Q L Q I A K K L S K G I 1480 CGC CCG GTT CTG GGG CAG CCG GAG GAA GTG CAG TTC CGG CGA CTG CAG GCG CTC ATG ATG 4500 R P V L G Q P E E V Q F R R L Q A L M M 1500 GAG TGC TGG GAC ACT AAG CCA GAG AAG CGA CCG CTG GCC CTG TCG GTG GTG AGC CAG ATG 4560 E C W D T K P E K R P L A L S V V S Q M 1520 AAG GAC CCG ACT TTT GCC ACC TTC ATG TAT GAA CTG TGC TGT GGG AAG CAG ACA GCC TTC 4620 K D P T F A T F M Y E L C C G K Q T A F 1540 TTC TCA TCC CAG GGC CAG GAG TAC ACC GTG GTG TTT TGG GAT GGA AAA GAG GAG TCC AGG 4680 F S S Q G Q E Y T V V F W D G K E E S R 1560 AAC TAC ACG GTG GTG AAC ACA GAG AAG GGC CTC ATG GAG GTG CAG AGG ATG TGC TGC CCT 4740 N Y T V V N T E K G L M E V Q R M C C P 1580 GGG ATG AAG GTG AGC TGC CAG CTC CAG GTC CAG AGA TCC CTG TGG ACA GCC ACC GAG GAC 4800 G M K V S C Q L Q V Q R S L W T A T E D 1600 CAG AAA ATC TAC ATC TAC ACC CTC AAG GGC ATG TGC CCC TTA AAC ACA CCC CAA CAG GCC 4860 Q K I Y I Y T L K G M C P L N T P Q Q A 1620 TTG GAT ACT CCA GCT GTC GTC ACC TGC TTC TTG GCC GTG CCT GTT ATT AAA AAG AAT TCC 4920 L D T P A V V T C F L A V P V I K K N S 1640 TAC CTG GTC TTA GCG GGC CTC GCC GAT GGG CTT GTG GCT GTG TTT CCC GTG GTG CGG GGC 4980 Y L V L A G L A D G L V A V F P V V R G 1660 ACC CCA AAG GAC AGC TGC TCC TAC CTG TGC TCA CAC ACA GCC AAC AGG TCC AAG TTC AGC 5040 T P K D S C S Y L C S H T A N R S K F S 1680 ATC GCG GAT GAA GAC GCA CGG CAG AAC CCC TAC CCA GTG AAG GCC ATG GAG GTG GTC AAC 5100 I A D E D A R Q N P Y P V K A M E V V N 1700 AGC GGC TCT GAG GTC TGG TAC AGC AAT GGG CCG GGC CTC CTT GTC ATC GAC TGT GCC TCC 5160 S G S E V W Y S N G P G L L V I D C A S 1720 CTG GAG ATC TGC AGG CGG CTG GAG CCC TAC ATG GCC CCC TCC ATG GTT ACG TCA GTC GTG 5220 L E I C R R L E P Y M A P S M V T S V V 1740 TGC AGC TCT GAG GGC AGA GGG GAG GAG GTC GTC TGG TGC CTG GAT GAC AAG GCC AAC TCC 5280 C S S E G R G E E V V W C L D D K A N S 1760 TTG GTG ATG TAC CAC TCC ACC ACC TAC CAG CTG TGT GCC CGG TAC TTC TGC GGG GTC CCC 5340 L V M Y H S T T Y Q L C A R Y F C G V P 1780 AGC CCC CTC AGG GAC ATG TTT CCC GTG CGG CCC TTG GAC ACG GAA CCC CCG GCA GCC AGC 5400 S P L R D M F P V R P L D T E P P A A S 1800 CAC ACG GCC AAC CCA AAG GTG CCT GAG GGG GAC TCC ATC GCG GAC GTG AGC ATC ATG TAC 5460 H T A N P K V P E G D S I A D V S I M Y 1820 AGT GAG GAG CTG GGC ACG CAG ATC CTG ATC CAC CAG GAA TCA CTC ACT GAC TAC TGC TCC 5520 S E E L G T Q I L I H Q E S L T D Y C S 1840 ATG TCC TCC TAC TCC TCA TCC CCA CCC CGC CAG GCT GCC AGG TCC CCC TCA AGC CTC CCC 5580 M S S Y S S S P P R Q A A R S P S S L P 1860 AGC TCC CCA GCA AGT TCT TCC AGT GTG CCT TTC TCC ACC GAC TGC GAG GAC TCA GAC ATG 5640 S S P A S S S S V P F S T D C E D S D M 1880 CTA CAT ACG CCC GGT GCT GCC TCC GAC AGG TCT GAG CAT GAC CTG ACC CCC ATG GAC GGG 5700 L H T P G A A S D R S E H D L T P M D G 1900 GAG ACC TTC AGC CAG CAC CTG CAG GCC GTG AAG ATC CTC GCC GTC AGA GAC CTC ATT TGG 5760 E T F S Q H L Q A V K I L A V R D L I W 1920 GTC CCC AGG CGC GGT GGA GAT GTT ATC GTC ATT GGC CTG GAG AAG GAT TCT GGC GCC CAG 5820 V P R R G G D V I V I G L E K D S G A Q 1940 CGG GGC CGA GTC ATT GCC GTC TTA AAA GCC CGA GAG CTG ACT CCG CAT GGG GTG CTG GTG 5880 R G R V I A V L K A R E L T P H G V L V 1960 GAT GCT GCC GTG GTG GCA AAG GAC ACT GTT GTG TGC ACC TTT GAA AAT GAA AAC ACA GAG 5940 D A A V V A K D T V V C T F E N E N T E 1980 TGG TGC CTG GCC GTC TGG AGG GGC TGG GGC GCC AGG GAG TTC GAC ATT TTC TAC CAG TCC 6000 W C L A V W R G W G A R E F D I F Y Q S 2000 TAC GAG GAG CTG GGC CGG CTG GAG GCT TGC ACT CGC AAG AGA AGG TAA 6048 Y E E L G R L E A C T R K R R * 2016