IRS1 atg gcg agc cct ccg gag agc gat ggc ttc tcg gac gtg cgc aag gtg ggc tac ctg cgc 60 M A S P P E S D G F S D V R K V G Y L R 20 aaa ccc aag agc atg cac aaa cgc ttc ttc gta ctg cgc gcg gcc agc gag gct ggg ggc 120 K P K S M H K R F F V L R A A S E A G G 40 ccg gcg cgc ctc gag tac tac gag aac gag aag aag tgg cgg cac aag tcg agc gcc ccc 180 P A R L E Y Y E N E K K W R H K S S A P 60 aaa cgc tcg atc ccc ctt gag agc tgc ttc aac atc aac aag cgg gct gac tcc aag aac 240 K R S I P L E S C F N I N K R A D S K N 80 aag cac ctg gtg gct ctc tac acc cgg gac gag cac ttt gcc atc gcg gcg gac agc gag 300 K H L V A L Y T R D E H F A I A A D S E 100 gcc gag caa gac agc tgg tac cag gct ctc cta cag ctg cac aac cgt gct aag ggc cac 360 A E Q D S W Y Q A L L Q L H N R A K G H 120 cac gac gga gct gcg gcc ctc ggg gcg gga ggt ggt ggg ggc agc tgc agc ggc agc tcc 420 H D G A A A L G A G G G G G S C S G S S 140 ggc ctt ggt gag gct ggg gag gac ttg agc tac ggt gac gtg ccc cca gga ccc gca ttc 480 G L G E A G E D L S Y G D V P P G P A F 160 aaa gag gtc tgg caa gtg atc ctg aag ccc aag ggc ctg ggt cag aca aag aac ctg att 540 K E V W Q V I L K P K G L G Q T K N L I 180 ggt atc tac cgc ctt tgc ctg acc agc aag acc atc agc ttc gtg aag ctg aac tcg gag 600 G I Y R L C L T S K T I S F V K L N S E 200 gca gcg gcc gtg gtg ctg cag ctg atg aac atc agg cgc tgt ggc cac tcg gaa aac ttc 660 A A A V V L Q L M N I R R C G H S E N F 220 ttc ttc atc gag gtg ggc cgt tct gcc gtg acg ggg ccc ggg gag ttc tgg atg cag gtg 720 F F I E V G R S A V T G P G E F W M Q V 240 gat gac tct gtg gtg gcc cag aac atg cac gag acc atc ctg gag gcc atg cgg gcc atg 780 D D S V V A Q N M H E T I L E A M R A M 260 agt gat gag ttc cgc cct cgc agc aag agc cag tcc tcg tcc aac tgc tct aac ccc atc 840 S D E F R P R S K S Q S S S N C S N P I 280 agc gtc ccc ctg cgc cgg cac cat ctc aac aat ccc ccg ccc agc cag gtg ggg ctg acc 900 S V P L R R H H L N N P P P S Q V G L T 300 cgc cga tca cgc act gag agc atc acc gcc acc tcc ccg gcc agc atg gtg ggc ggg aag 960 R R S R T E S I T A T S P A S M V G G K 320 cca ggc tcc ttc cgt gtc cgc gcc tcc agt gac ggc gaa ggc acc atg tcc cgc cca gcc 1020 P G S F R V R A S S D G E G T M S R P A 340 tcg gtg gac ggc agc cct gtg agt ccc agc acc aac aga acc cac gcc cac cgg cat cgg 1080 S V D G S P V S P S T N R T H A H R H R 360 ggc agc gcc cgg ctg cac ccc ccg ctc aac cac agc cgc tcc atc ccc atg ccg gct tcc 1140 G S A R L H P P L N H S R S I P M P A S 380 cgc tgc tcg cct tcg gcc acc agc ccg gtc agt ctg tcg tcc agt agc acc agt ggc cat 1200 R C S P S A T S P V S L S S S S T S G H 400 ggc tcc acc tcg gat tgt ctc ttc cca cgg cga tct agt gct tcg gtg tct ggt tcc ccc 1260 G S T S D C L F P R R S S A S V S G S P 420 agc gat ggc ggt ttc atc tcc tcg gat gag tat ggc tcc agt ccc tgc gat ttc cgg agt 1320 S D G G F I S S D E Y G S S P C D F R S 440 tcc ttc cgc agt gtc act ccg gat tcc ctg ggc cac acc cca cca gcc cgc ggt gag gag 1380 S F R S V T P D S L G H T P P A R G E E 460 gag cta agc aac tat atc tgc atg ggt ggc aag ggg ccc tcc acc ctg acc gcc ccc aac 1440 E L S N Y I C M G G K G P S T L T A P N 480 ggt cac tac att ttg tct cgg ggt ggc aat ggc cac cgc tgc acc cca gga aca ggc ttg 1500 G H Y I L S R G G N G H R C T P G T G L 500 ggc acg agt cca gcc ttg gct ggg gat gaa gca gcc agt gct gca gat ctg gat aat cgg 1560 G T S P A L A G D E A A S A A D L D N R 520 ttc cga aag aga act cac tcg gca ggc aca tcc cct acc att acc cac cag aag acc ccg 1620 F R K R T H S A G T S P T I T H Q K T P 540 tcc cag tcc tca gtg gct tcc att gag gag tac aca gag atg atg cct gcc tac cca cca 1680 S Q S S V A S I E E Y T E M M P A Y P P 560 gga ggt ggc agt gga ggc cga ctg ccg gga cac agg cac tcc gcc ttc gtg ccc acc cgc 1740 G G G S G G R L P G H R H S A F V P T R 580 tcc tac cca gag gag ggt ctg gaa atg cac ccc ttg gag cgt cgg ggg ggg cac cac cgc 1800 S Y P E E G L E M H P L E R R G G H H R 600 cca gac agc tcc acc ctc cac acg gat gat ggc tac atg ccc atg tcc cca ggg gtg gcc 1860 P D S S T L H T D D G Y M P M S P G V A 620 cca gtg ccc agt ggc cga aag ggc agt gga gac tat atg ccc atg agc ccc aag agc gta 1920 P V P S G R K G S G D Y M P M S P K S V 640 tct gcc cca cag cag atc atc aat ccc atc aga cgc cat ccc cag aga gtg gac ccc aat 1980 S A P Q Q I I N P I R R H P Q R V D P N 660 ggc tac atg atg atg tcc ccc agc ggt ggc tgc tct cct gac att gga ggt ggc ccc agc 2040 G Y M M M S P S G G C S P D I G G G P S 680 agc agc agc agc agc agc aac gcc gtc cct tcc ggg acc agc tat gga aag ctg tgg aca 2100 S S S S S S N A V P S G T S Y G K L W T 700 aac ggg gta ggg ggc cac cac tct cat gtc ttg cct cac ccc aaa ccc cca gtg gag agc 2160 N G V G G H H S H V L P H P K P P V E S 720 agc ggt ggt aag ctc tta cct tgc aca ggt gac tac atg aac atg tca cca gtg ggg gac 2220 S G G K L L P C T G D Y M N M S P V G D 740 tcc aac acc agc agc ccc tcc gac tgc tac tac ggc cct gag gac ccc cag cac aag cca 2280 S N T S S P S D C Y Y G P E D P Q H K P 760 gtc ctc tcc tac tac tca ttg cca aga tcc ttt aag cac acc cag cgc ccc ggg gag ccg 2340 V L S Y Y S L P R S F K H T Q R P G E P 780 gag gag ggt gcc cgg cat cag cac ctc cgc ctt tcc act agc tct ggt cgc ctt ctc tat 2400 E E G A R H Q H L R L S T S S G R L L Y 800 gct gca aca gca gat gat tct tcc tct tcc acc agc agc gac agc ctg ggt ggg gga tac 2460 A A T A D D S S S S T S S D S L G G G Y 820 tgc ggg gct agg ctg gag ccc agc ctt cca cat ccc cac cat cag gtt ctg cag ccc cat 2520 C G A R L E P S L P H P H H Q V L Q P H 840 ctg cct cga aag gtg gac aca gct gct cag acc aat agc cgc ctg gcc cgg ccc acg agg 2580 L P R K V D T A A Q T N S R L A R P T R 860 ctg tcc ctg ggg gat ccc aag gcc agc acc tta cct cgg gcc cga gag cag cag cag cag 2640 L S L G D P K A S T L P R A R E Q Q Q Q 880 cag cag ccc ttg ctg cac cct cca gag ccc aag agc ccg ggg gaa tat gtc aat att gaa 2700 Q Q P L L H P P E P K S P G E Y V N I E 900 ttt ggg agt gat cag tct ggc tac ttg tct ggc ccg gtg gct ttc cac agc tca cct tct 2760 F G S D Q S G Y L S G P V A F H S S P S 920 gtc agg tgt cca tcc cag ctc cag cca gct ccc aga gag gaa gag act ggc act gag gag 2820 V R C P S Q L Q P A P R E E E T G T E E 940 tac atg aag atg gac ctg ggg ccg ggc cgg agg gca gcc tgg cag gag agc act ggg gtc 2880 Y M K M D L G P G R R A A W Q E S T G V 960 gag atg ggc aga ctg ggc cct gca cct ccc ggg gct gct agc att tgc agg cct acc cgg 2940 E M G R L G P A P P G A A S I C R P T R 980 gca gtg ccc agc agc cgg ggt gac tac atg acc atg cag atg agt tgt ccc cgt cag agc 3000 A V P S S R G D Y M T M Q M S C P R Q S 1000 tac gtg gac acc tcg cca gct gcc cct gta agc tat gct gac atg cga aca ggc att gct 3060 Y V D T S P A A P V S Y A D M R T G I A 1020 gca gag gag gtg agc ctg ccc agg gcc acc atg gct gct gcc tcc tca tcc tca gca gcc 3120 A E E V S L P R A T M A A A S S S S A A 1040 tct gct tcc ccg act ggg cct caa ggg gca gca gag ctg gct gcc cac tcg tcc ctg ctg 3180 S A S P T G P Q G A A E L A A H S S L L 1060 ggg ggc cca caa gga cct ggg ggc atg agc gcc ttc acc cgg gtg aac ctc agt cct aac 3240 G G P Q G P G G M S A F T R V N L S P N 1080 cgc aac cag agt gcc aaa gtg atc cgt gca gac cca caa ggg tgc cgg cgg agg cat agc 3300 R N Q S A K V I R A D P Q G C R R R H S 1100 tcc gag act ttc tcc tca aca ccc agt gcc acc cgg gtg ggc aac aca gtg ccc ttt gga 3360 S E T F S S T P S A T R V G N T V P F G 1120 gcg ggg gca gca gta ggg ggc ggt ggc ggt agc agc agc agc agc gag gat gtg aaa cgc 3420 A G A A V G G G G G S S S S S E D V K R 1140 cac agc tct gct tcc ttt gag aat gtg tgg ctg agg cct ggg gag ctt ggg gga gcc ccc 3480 H S S A S F E N V W L R P G E L G G A P 1160 aag gag cca gcc aaa ctg tgt ggg gct gct ggg ggt ttg gag aat ggt ctt aac tac ata 3540 K E P A K L C G A A G G L E N G L N Y I 1180 gac ctg gat ttg gtc aag gac ttc aaa cag tgc cct cag gag tgc acc cct gaa ccg cag 3600 D L D L V K D F K Q C P Q E C T P E P Q 1200 cct ccc cca ccc cca ccc cct cat caa ccc ctg ggc agc ggt gag agc agc tcc acc cgc 3660 P P P P P P P H Q P L G S G E S S S T R 1220 cgc tca agt gag gat tta agc gcc tat gcc agc atc agt ttc cag aag cag cca gag gac 3720 R S S E D L S A Y A S I S F Q K Q P E D 1240 cgt cag tag 3729 R Q * 1243