ADAMTS3 ATG GTT CTC CTG TCA CTT TGG TTG ATA GCA GCC GCT CTG GTA GAG GTT AGG ACT TCA GCT 60 M V L L S L W L I A A A L V E V R T S A 20 GAT GGA CAA GCT GGT AAT GAA GAA ATG GTG CAA ATA GAT TTA CCA ATA AAG AGA TAT AGA 120 D G Q A G N E E M V Q I D L P I K R Y R 40 GAG TAT GAG CTG GTG ACT CCA GTC AGC ACA AAT CTA GAA GGA CGC TAT CTC TCC CAT ACT 180 E Y E L V T P V S T N L E G R Y L S H T 60 CTT TCT GCG AGT CAC AAA AAG AGG TCA GCG AGG GAC GTG TCT TCC AAC CCT GAG CAG TTG 240 L S A S H K K R S A R D V S S N P E Q L 80 TTC TTT AAC ATC ACG GCA TTT GGA AAA GAT TTT CAT CTG CGA CTA AAG CCC AAC ACT CAA 300 F F N I T A F G K D F H L R L K P N T Q 100 CTA GTA GCT CCT GGG GCT GTT GTG GAG TGG CAT GAG ACA TCT CTG GTG CCT GGG AAT ATA 360 L V A P G A V V E W H E T S L V P G N I 120 ACC GAT CCC ATT AAC AAC CAT CAA CCA GGA AGT GCT ACG TAT AGA ATC CGG AGA ACA GAG 420 T D P I N N H Q P G S A T Y R I R R T E 140 CCT TTG CAG ACT AAC TGT GCT TAT GTT GGT GAC ATC GTG GAC ATT CCA GGA ACC TCT GTT 480 P L Q T N C A Y V G D I V D I P G T S V 160 GCC ATC AGC AAC TGT GAT GGT CTG GCT GGA ATG ATA AAA AGT GAT AAT GAA GAG TAT TTC 540 A I S N C D G L A G M I K S D N E E Y F 180 ATT GAA CCC TTG GAA AGA GGT AAA CAG ATG GAG GAA GAA AAA GGA AGG ATT CAT GTT GTC 600 I E P L E R G K Q M E E E K G R I H V V 200 TAC AAG AGA TCA GCT GTA GAA CAG GCT CCC ATA GAC ATG TCC AAA GAC TTC CAC TAC AGA 660 Y K R S A V E Q A P I D M S K D F H Y R 220 GAG TCG GAC CTG GAA GGC CTT GAT GAT CTA GGT ACT GTT TAT GGC AAC ATC CAC CAG CAG 720 E S D L E G L D D L G T V Y G N I H Q Q 240 CTG AAT GAA ACA ATG AGA CGC CGC AGA CAC GCG GGA GAA AAC GAT TAC AAT ATC GAG GTA 780 L N E T M R R R R H A G E N D Y N I E V 260 CTG CTG GGA GTG GAT GAC TCT GTG GTC CGT TTC CAT GGC AAA GAG CAC GTC CAA AAC TAC 840 L L G V D D S V V R F H G K E H V Q N Y 280 CTC CTG ACC CTA ATG AAC ATT GTG AAT GAA ATT TAC CAT GAT GAG TCC CTC GGA GTG CAT 900 L L T L M N I V N E I Y H D E S L G V H 300 ATA AAT GTG GTC CTG GTG CGC ATG ATA ATG CTG GGA TAT GCA AAG TCC ATC AGC CTC ATA 960 I N V V L V R M I M L G Y A K S I S L I 320 GAA AGG GGA AAC CCA TCC AGA AGC TTG GAG AAT GTG TGT CGC TGG GCG TCC CAA CAG CAA 1020 E R G N P S R S L E N V C R W A S Q Q Q 340 AGA TCT GAT CTC AAC CAC TCT GAA CAC CAT GAC CAT GCA ATT TTT TTA ACC AGG CAA GAC 1080 R S D L N H S E H H D H A I F L T R Q D 360 TTT GGA CCT GCT GGA ATG CAA GGA TAT GCT CCA GTC ACC GGC ATG TGT CAT CCA GTG AGA 1140 F G P A G M Q G Y A P V T G M C H P V R 380 AGT TGT ACC CTG AAT CAT GAG GAT GGT TTT TCA TCT GCT TTT GTA GTA GCC CAT GAA ACG 1200 S C T L N H E D G F S S A F V V A H E T 400 GGC CAT GTG TTG GGA ATG GAG CAT GAT GGA CAA GGC AAC AGG TGT GGT GAT GAG ACT GCT 1260 G H V L G M E H D G Q G N R C G D E T A 420 ATG GGA AGT GTC ATG GCT CCC TTG GTA CAA GCA GCA TTC CAT CGT TAC CAC TGG TCC CGA 1320 M G S V M A P L V Q A A F H R Y H W S R 440 TGC AGT GGT CAA GAA CTG AAA AGA TAT ATC CAT TCC TAT GAC TGT CTC CTT GAT GAC CCT 1380 C S G Q E L K R Y I H S Y D C L L D D P 460 TTT GAT CAT GAT TGG CCT AAA CTC CCA GAA CTT CCT GGA ATC AAT TAT TCT ATG GAT GAG 1440 F D H D W P K L P E L P G I N Y S M D E 480 CAA TGT CGT TTT GAT TTT GGT GTT GGC TAT AAA ATG TGC ACC GCG TTC CGA ACC TTT GAC 1500 Q C R F D F G V G Y K M C T A F R T F D 500 CCA TGT AAA CAG CTG TGG TGT AGC CAT CCT GAT AAT CCC TAC TTT TGT AAG ACT AAA AAG 1560 P C K Q L W C S H P D N P Y F C K T K K 520 GGA CCT CCA CTT GAT GGG ACT GAA TGT GCT GCT GGA AAA TGG TGC TAT AAG GGT CAT TGC 1620 G P P L D G T E C A A G K W C Y K G H C 540 ATG TGG AAG AAT GCT AAT CAG CAA AAA CAA GAT GGC AAT TGG GGG TCA TGG ACT AAA TTT 1680 M W K N A N Q Q K Q D G N W G S W T K F 560 GGC TCC TGT TCT CGG ACA TGT GGA ACT GGT GTT CGT TTC AGA ACA CGC CAG TGC AAT AAT 1740 G S C S R T C G T G V R F R T R Q C N N 580 CCC ATG CCC ATC AAT GGT GGT CAG GAT TGT CCT GGT GTT AAT TTT GAG TAC CAG CTT TGT 1800 P M P I N G G Q D C P G V N F E Y Q L C 600 AAC ACA GAA GAA TGC CAA AAA CAC TTT GAG GAC TTC AGA GCA CAG CAG TGT CAG CAG CGA 1860 N T E E C Q K H F E D F R A Q Q C Q Q R 620 AAC TCC CAC TTT GAA TAC CAG AAT ACC AAA CAC CAC TGG TTG CCA TAT GAA CAT CCT GAC 1920 N S H F E Y Q N T K H H W L P Y E H P D 640 CCC AAG AAA AGA TGC CAC CTT TAC TGT CAG TCC AAG GAG ACT GGA GAT GTT GCT TAC ATG 1980 P K K R C H L Y C Q S K E T G D V A Y M 660 AAA CAA CTG GTG CAT GAT GGA ACG CAC TGT TCT TAC AAA GAT CCA TAT AGC ATA TGT GTG 2040 K Q L V H D G T H C S Y K D P Y S I C V 680 CGA GGA GAG TGT GTG AAA GTG GGC TGT GAT AAA GAA ATT GGT TCT AAT AAG GTT GAG GAT 2100 R G E C V K V G C D K E I G S N K V E D 700 AAG TGT GGT GTC TGT GGA GGA GAT AAT TCC CAC TGC CGA ACC GTG AAG GGG ACA TTT ACC 2160 K C G V C G G D N S H C R T V K G T F T 720 AGA ACT CCC AGG AAG CTT GGG TAC CTT AAG ATG TTT GAT ATA CCC CCT GGG GCT AGA CAT 2220 R T P R K L G Y L K M F D I P P G A R H 740 GTG TTA ATC CAA GAA GAC GAG GCT TCT CCT CAT ATT CTT GCT ATT AAG AAC CAG GCT ACA 2280 V L I Q E D E A S P H I L A I K N Q A T 760 GGC CAT TAT ATT TTA AAT GGC AAA GGG GAG GAA GCC AAG TCG CGG ACC TTC ATA GAT CTT 2340 G H Y I L N G K G E E A K S R T F I D L 780 GGT GTG GAG TGG GAT TAT AAC ATT GAA GAT GAC ATT GAA AGT CTT CAC ACC GAT GGA CCT 2400 G V E W D Y N I E D D I E S L H T D G P 800 TTA CAT GAT CCT GTT ATT GTT TTG ATT ATA CCT CAA GAA AAT GAT ACC CGC TCT AGC CTG 2460 L H D P V I V L I I P Q E N D T R S S L 820 ACA TAT AAG TAC ATC ATC CAT GAA GAC TCT GTA CCT ACA ATC AAC AGC AAC AAT GTC ATC 2520 T Y K Y I I H E D S V P T I N S N N V I 840 CAG GAA GAA TTA GAT ACT TTT GAG TGG GCT TTG AAG AGC TGG TCT CAG TGT TCC AAA CCC 2580 Q E E L D T F E W A L K S W S Q C S K P 860 TGT GGT GGA GGT TTC CAG TAC ACT AAA TAT GGA TGC CGT AGG AAA AGT GAT AAT AAA ATG 2640 C G G G F Q Y T K Y G C R R K S D N K M 880 GTC CAT CGC AGC TTC TGT GAG GCC AAC AAA AAG CCG AAA CCT ATT AGA CGA ATG TGC AAT 2700 V H R S F C E A N K K P K P I R R M C N 900 ATT CAA GAG TGT ACA CAT CCA CTC TGG GTA GCA GAA GAA TGG GAA CAC TGC ACC AAA ACC 2760 I Q E C T H P L W V A E E W E H C T K T 920 TGT GGA AGT TCT GGC TAT CAG CTT CGC ACT GTA CGC TGC CTT CAG CCA CTC CTT GAT GGC 2820 C G S S G Y Q L R T V R C L Q P L L D G 940 ACC AAC CGC TCT GTG CAC AGC AAA TAC TGC ATG GGT GAC CGT CCC GAG AGC CGC CGG CCC 2880 T N R S V H S K Y C M G D R P E S R R P 960 TGT AAC AGA GTG CCC TGC CCT GCA CAG TGG AAA ACA GGA CCC TGG AGT GAG TGT TCA GTG 2940 C N R V P C P A Q W K T G P W S E C S V 980 ACC TGC GGT GAA GGA ACG GAG GTG AGG CAG GTC CTC TGC AGG GCT GGG GAC CAC TGT GAT 3000 T C G E G T E V R Q V L C R A G D H C D 1000 GGT GAA AAG CCT GAG TCG GTC AGA GCC TGT CAA CTG CCT CCT TGT AAT GAT GAA CCA TGT 3060 G E K P E S V R A C Q L P P C N D E P C 1020 TTG GGA GAC AAG TCC ATA TTC TGT CAA ATG GAA GTG TTG GCA CGA TAC TGC TCC ATA CCA 3120 L G D K S I F C Q M E V L A R Y C S I P 1040 GGT TAT AAC AAG TTA TGT TGT GAG TCC TGC AGC AAG CGC AGT AGC ACC CTG CCA CCA CCA 3180 G Y N K L C C E S C S K R S S T L P P P 1060 TAC CTT CTA GAA GCT GCT GAA ACT CAT GAT GAT GTC ATC TCT AAC CCT AGT GAC CTC CCT 3240 Y L L E A A E T H D D V I S N P S D L P 1080 AGA TCT CTA GTG ATG CCT ACA TCT TTG GTT CCT TAT CAT TCA GAG ACC CCT GCA AAG AAG 3300 R S L V M P T S L V P Y H S E T P A K K 1100 ATG TCT TTG AGT AGC ATC TCT TCA GTG GGA GGT CCA AAT GCA TAT GCT GCT TTC AGG CCA 3360 M S L S S I S S V G G P N A Y A A F R P 1120 AAC AGT AAA CCT GAT GGT GCT AAT TTA CGC CAG AGG AGT GCT CAG CAA GCA GGA AGT AAG 3420 N S K P D G A N L R Q R S A Q Q A G S K 1140 ACT GTG AGA CTG GTC ACC GTA CCA TCC TCC CCA CCC ACC AAG AGG GTC CAC CTC AGT TCA 3480 T V R L V T V P S S P P T K R V H L S S 1160 GCT TCA CAA ATG GCT GCT GCT TCC TTC TTT GCA GCC AGT GAT TCA ATA GGT GCT TCT TCT 3540 A S Q M A A A S F F A A S D S I G A S S 1180 CAG GCA AGA ACC TCA AAG AAA GAT GGA AAG ATC ATT GAC AAC AGA CGT CCG ACA AGA TCA 3600 Q A R T S K K D G K I I D N R R P T R S 1200 TCC ACC TTA GAA AGA TGA 3618 S T L E R * 1206