ADAMTS16 ATG AAG CCC CGC GCG CGC GGA TGG CGG GGC TTG GCG GCG CTG TGG ATG CTG TTG GCG CAG 60 M K P R A R G W R G L A A L W M L L A Q 20 GTG GCC GAG CAG GCA CCT GCG TGC GCC ATG GGA CCC GCA GCG GCA GCG CCT GGG AGC CCG 120 V A E Q A P A C A M G P A A A A P G S P 40 AGC GTC CCG CGT CCT CCT CCA CCC GCG GAG CGG CCG GGC TGG ATG GAA AAG GGC GAA TAT 180 S V P R P P P P A E R P G W M E K G E Y 60 GAC CTG GTC TCT GCC TAC GAG GTT GAC CAC AGG GGC GAT TAC GTG TCC CAT GAA ATC ATG 240 D L V S A Y E V D H R G D Y V S H E I M 80 CAC CAT CAG CGG CGG AGA AGA GCA GTG CCC GTG TCC GAG GTT GAG TCT CTT CAC CTT CGG 300 H H Q R R R R A V P V S E V E S L H L R 100 CTG AAA GGC TCC AGG CAC GAC TTC CAC ATG GAT CTG AGG ACT TCC AGC AGC CTA GTG GCT 360 L K G S R H D F H M D L R T S S S L V A 120 CCT GGC TTT ATT GTG CAG ACG TTG GGA AAG ACA GGC ACT AAG TCT GTG CAG ACT TTA CCG 420 P G F I V Q T L G K T G T K S V Q T L P 140 CCA GAG GAC TTC TGT TTC TAT CAA GGC TCT TTG CGA TCA CAC AGA AAC TCC TCA GTG GCC 480 P E D F C F Y Q G S L R S H R N S S V A 160 CTT TCA ACC TGC CAA GGC TTG TCA GGC ATG ATA CGA ACA GAA GAG GCA GAT TAC TTC CTA 540 L S T C Q G L S G M I R T E E A D Y F L 180 AGG CCA CTT CCT TCA CAC CTC TCA TGG AAA CTC GGC AGA GCT GCC CAA GGC AGC TCG CCA 600 R P L P S H L S W K L G R A A Q G S S P 200 TCC CAC GTA CTG TAC AAG AGA TCC ACA GAG CCC CAT GCT CCT GGG GCC AGT GAG GTC CTG 660 S H V L Y K R S T E P H A P G A S E V L 220 GTG ACC TCA AGG ACA TGG GAG CTG GCA CAT CAA CCC CTG CAC AGC AGC GAC CTT CGC CTG 720 V T S R T W E L A H Q P L H S S D L R L 240 GGA CTG CCA CAA AAG CAG CAT TTC TGT GGA AGA CGC AAG AAA TAC ATG CCC CAG CCT CCC 780 G L P Q K Q H F C G R R K K Y M P Q P P 260 AAG GAA GAC CTC TTC ATC TTG CCA GAT GAG TAT AAG TCT TGC TTA CGG CAT AAG CGC TCT 840 K E D L F I L P D E Y K S C L R H K R S 280 CTT CTG AGG TCC CAT AGA AAT GAA GAA CTG AAC GTG GAG ACC TTG GTG GTG GTC GAC AAA 900 L L R S H R N E E L N V E T L V V V D K 300 AAG ATG ATG CAA AAC CAT GGC CAT GAA AAT ATC ACC ACC TAC GTG CTC ACG ATA CTC AAC 960 K M M Q N H G H E N I T T Y V L T I L N 320 ATG GTA TCT GCT TTA TTC AAA GAT GGA ACA ATA GGA GGA AAC ATC AAC ATT GCA ATT GTA 1020 M V S A L F K D G T I G G N I N I A I V 340 GGT CTG ATT CTT CTA GAA GAT GAA CAG CCA GGA CTG GTG ATA AGT CAC CAC GCA GAC CAC 1080 G L I L L E D E Q P G L V I S H H A D H 360 ACC TTA AGT AGC TTC TGC CAG TGG CAG TCT GGA TTG ATG GGG AAA GAT GGG ACT CGT CAT 1140 T L S S F C Q W Q S G L M G K D G T R H 380 GAC CAC GCC ATC TTA CTG ACT GGT CTG GAT ATA TGT TCC TGG AAG AAT GAG CCC TGT GAC 1200 D H A I L L T G L D I C S W K N E P C D 400 ACT TTG GGA TTT GCA CCC ATA AGT GGA ATG TGT AGT AAA TAT CGC AGC TGC ACG ATT AAT 1260 T L G F A P I S G M C S K Y R S C T I N 420 GAA GAT ACA GGT CTT GGA CTG GCC TTC ACC ATT GCC CAT GAG TCT GGA CAC AAC TTT GGC 1320 E D T G L G L A F T I A H E S G H N F G 440 ATG ATT CAT GAT GGA GAA GGG AAC ATG TGC AAA AAG TCC GAG GGC AAC ATC ATG TCC CCT 1380 M I H D G E G N M C K K S E G N I M S P 460 ACA TTG GCA GGA CGC AAT GGA GTC TTC TCC TGG TCA CCC TGC AGC CGC CAG TAT CTA CAC 1440 T L A G R N G V F S W S P C S R Q Y L H 480 AAA TTT CTA AGC ACC GCT CAA GCT ATC TGC CTT GCT GAT CAG CCA AAG CCT GTG AAG GAA 1500 K F L S T A Q A I C L A D Q P K P V K E 500 TAC AAG TAT CCT GAG AAA TTG CCA GGA GAA TTA TAT GAT GCA AAC ACA CAG TGC AAG TGG 1560 Y K Y P E K L P G E L Y D A N T Q C K W 520 CAG TTC GGA GAG AAA GCC AAG CTC TGC ATG CTG GAC TTT AAA AAG GAC ATC TGT AAA GCC 1620 Q F G E K A K L C M L D F K K D I C K A 540 CTG TGG TGC CAT CGT ATT GGA AGG AAA TGT GAG ACT AAA TTT ATG CCA GCA GCA GAA GGC 1680 L W C H R I G R K C E T K F M P A A E G 560 ACA ATT TGT GGG CAT GAC ATG TGG TGC CGG GGA GGA CAG TGT GTG AAA TAT GGT GAT GAA 1740 T I C G H D M W C R G G Q C V K Y G D E 580 GGC CCC AAG CCC ACC CAT GGC CAC TGG TCG GAC TGG TCT TCT TGG TCC CCA TGC TCC AGG 1800 G P K P T H G H W S D W S S W S P C S R 600 ACC TGC GGA GGG GGA GTA TCT CAT AGG AGT CGC CTC TGC ACC AAC CCC AAG CCA TCG CAT 1860 T C G G G V S H R S R L C T N P K P S H 620 GGA GGG AAG TTC TGT GAG GGC TCC ACT CGC ACT CTG AAG CTC TGC AAC AGT CAG AAA TGT 1920 G G K F C E G S T R T L K L C N S Q K C 640 CCC CGG GAC AGT GTT GAC TTC CGT GCT GCT CAG TGT GCC GAG CAC AAC AGC AGA CGA TTC 1980 P R D S V D F R A A Q C A E H N S R R F 660 AGA GGG CGG CAC TAC AAG TGG AAG CCT TAC ACT CAA GTA GAA GAT CAG GAC TTA TGC AAA 2040 R G R H Y K W K P Y T Q V E D Q D L C K 680 CTC TAC TGT ATC GCA GAA GGA TTT GAT TTC TTC TTT TCT TTG TCA AAT AAA GTC AAA GAT 2100 L Y C I A E G F D F F F S L S N K V K D 700 GGG ACT CCA TGC TCG GAG GAT AGC CGT AAT GTT TGT ATA GAT GGG ATA TGT GAG AGA GTT 2160 G T P C S E D S R N V C I D G I C E R V 720 GGA TGT GAC AAT GTC CTT GGA TCT GAT GCT GTT GAA GAC GTC TGT GGG GTG TGT AAC GGG 2220 G C D N V L G S D A V E D V C G V C N G 740 AAT AAC TCA GCC TGC ACG ATT CAC AGG GGT CTC TAC ACC AAG CAC CAC CAC ACC AAC CAG 2280 N N S A C T I H R G L Y T K H H H T N Q 760 TAT TAT CAC ATG GTC ACC ATT CCT TCT GGA GCC CGG AGT ATC CGC ATC TAT GAA ATG AAC 2340 Y Y H M V T I P S G A R S I R I Y E M N 780 GTC TCT ACC TCC TAC ATT TCT GTG CGC AAT GCC CTC AGA AGG TAC TAC CTG AAT GGG CAC 2400 V S T S Y I S V R N A L R R Y Y L N G H 800 TGG ACC GTG GAC TGG CCC GGC CGG TAC AAA TTT TCG GGC ACT ACT TTC GAC TAC AGA CGG 2460 W T V D W P G R Y K F S G T T F D Y R R 820 TCC TAT AAT GAG CCC GAG AAC TTA ATC GCT ACT GGA CCA ACC AAC GAG ACA CTG ATT GTG 2520 S Y N E P E N L I A T G P T N E T L I V 840 GAG CTG CTG TTT CAG GGA AGG AAC CCG GGT GTT GCC TGG GAA TAC TCC ATG CCT CGC TTG 2580 E L L F Q G R N P G V A W E Y S M P R L 860 GGG ACC GAG AAG CAG CCC CCT GCC CAG CCC AGC TAC ACT TGG GCC ATC GTG CGC TCT GAG 2640 G T E K Q P P A Q P S Y T W A I V R S E 880 TGC TCC GTG TCC TGC GGA GGG GGA CAG ATG ACC GTG AGA GAG GGC TGC TAC AGA GAC CTG 2700 C S V S C G G G Q M T V R E G C Y R D L 900 AAG TTT CAA GTA AAT ATG TCC TTC TGC AAT CCC AAG ACA CGA CCT GTC ACG GGG CTG GTG 2760 K F Q V N M S F C N P K T R P V T G L V 920 CCT TGC AAA GTA TCT GCC TGT CCT CCC AGC TGG TCC GTG GGG AAC TGG AGT GCC TGC AGT 2820 P C K V S A C P P S W S V G N W S A C S 940 CGG ACG TGT GGC GGG GGT GCC CAG AGC CGC CCC GTG CAG TGC ACA CGG CGG GTG CAC TAT 2880 R T C G G G A Q S R P V Q C T R R V H Y 960 GAC TCG GAG CCA GTC CCG GCC AGC CTG TGC CCT CAG CCT GCT CCC TCC AGC AGG CAG GCC 2940 D S E P V P A S L C P Q P A P S S R Q A 980 TGC AAC TCT CAG AGC TGC CCA CCT GCA TGG AGC GCC GGG CCC TGG GCA GAG TGC TCA CAC 3000 C N S Q S C P P A W S A G P W A E C S H 1000 ACC TGT GGG AAG GGG TGG AGG AAG CGG GCA GTG GCC TGT AAG AGC ACC AAC CCC TCG GCC 3060 T C G K G W R K R A V A C K S T N P S A 1020 AGA GCG CAG CTG CTG CCC GAC GCT GTC TGC ACC TCC GAG CCC AAG CCC AGG ATG CAT GAA 3120 R A Q L L P D A V C T S E P K P R M H E 1040 GCC TGT CTG CTT CAG CGC TGC CAC AAG CCC AAG AAG CTG CAG TGG CTG GTG TCC GCC TGG 3180 A C L L Q R C H K P K K L Q W L V S A W 1060 TCC CAG TGC TCT GTG ACA TGT GAA AGA GGA ACA CAG AAA AGA TTC TTA AAA TGT GCT GAA 3240 S Q C S V T C E R G T Q K R F L K C A E 1080 AAG TAT GTT TCT GGA AAG TAT CGA GAG CTG GCC TCA AAG AAG TGC TCA CAT TTG CCG AAG 3300 K Y V S G K Y R E L A S K K C S H L P K 1100 CCC AGC CTG GAG CTG GAA CGT GCC TGC GCC CCG CTT CCA TGC CCC AGG CAC CCC CCA TTT 3360 P S L E L E R A C A P L P C P R H P P F 1120 GCT GCT GCG GGA CCC TCG AGG GGC AGC TGG TTT GCC TCA CCC TGG TCT CAG TGC ACG GCC 3420 A A A G P S R G S W F A S P W S Q C T A 1140 AGC TGT GGG GGA GGC GTT CAG ACG AGG TCC GTG CAG TGC CTG GCT GGG GGC CGG CCG GCC 3480 S C G G G V Q T R S V Q C L A G G R P A 1160 TCA GGC TGC CTC CTG CAC CAG AAG CCT TCG GCC TCC CTG GCC TGC AAC ACT CAC TTC TGC 3540 S G C L L H Q K P S A S L A C N T H F C 1180 CCC ATT GCA GAG AAG AAA GAT GCC TTC TGC AAA GAC TAC TTC CAC TGG TGC TAC CTG GTA 3600 P I A E K K D A F C K D Y F H W C Y L V 1200 CCC CAG CAC GGG ATG TGC AGC CAC AAG TTC TAC GGC AAG CAG TGC TGC AAG ACT TGC TCT 3660 P Q H G M C S H K F Y G K Q C C K T C S 1220 AAG TCC AAC TTG TGA 3675 K S N L * 1225