ADAMTS12 ATG CCA TGT GCC CAG AGG AGC TGG CTT GCA AAC CTT TCC GTG GTG GCT CAG CTC CTT AAC 60 M P C A Q R S W L A N L S V V A Q L L N 20 TTT GGG GCG CTT TGC TAT GGG AGA CAG CCT CAG CCA GGC CCG GTT CGC TTC CCG GAC AGG 120 F G A L C Y G R Q P Q P G P V R F P D R 40 AGG CAA GAG CAT TTT ATC AAG GGC CTG CCA GAA TAC CAC GTG GTG GGT CCA GTC CGA GTA 180 R Q E H F I K G L P E Y H V V G P V R V 60 GAT GCC AGT GGG CAT TTT TTG TCA TAT GGC TTG CAC TAT CCC ATC ACG AGC AGC AGG AGG 240 D A S G H F L S Y G L H Y P I T S S R R 80 AAG AGA GAT TTG GAT GGC TCA GAG GAC TGG GTG TAC TAC AGA ATT TCT CAC GAG GAG AAG 300 K R D L D G S E D W V Y Y R I S H E E K 100 GAC CTG TTT TTT AAC TTG ACG GTC AAT CAA GGA TTT CTT TCC AAT AGC TAC ATC ATG GAG 360 D L F F N L T V N Q G F L S N S Y I M E 120 AAG AGA TAT GGG AAC CTC TCC CAT GTT AAG ATG ATG GCT TCC TCT GCC CCC CTC TGC CAT 420 K R Y G N L S H V K M M A S S A P L C H 140 CTC AGT GGC ACG GTT CTA CAG CAG GGC ACC AGA GTT GGG ACG GCA GCC CTC AGT GCC TGC 480 L S G T V L Q Q G T R V G T A A L S A C 160 CAT GGA CTG ACT GGA TTT TTC CAA CTA CCA CAT GGA GAC TTT TTC ATT GAA CCC GTG AAG 540 H G L T G F F Q L P H G D F F I E P V K 180 AAG CAT CCA CTG GTT GAG GGA GGG TAC CAC CCG CAC ATC GTT TAC AGG AGG CAG AAA GTT 600 K H P L V E G G Y H P H I V Y R R Q K V 200 CCA GAA ACC AAG GAG CCA ACC TGT GGA TTA AAG GAC AGT GTT AAC ATC TCC CAG AAG CAA 660 P E T K E P T C G L K D S V N I S Q K Q 220 GAG CTA TGG CGG GAG AAG TGG GAG AGG CAC AAC TTG CCA AGC AGA AGC CTC TCT CGG CGT 720 E L W R E K W E R H N L P S R S L S R R 240 TCC ATC AGC AAG GAG AGA TGG GTG GAG ACA CTG GTG GTG GCC GAC ACA AAG ATG ATT GAA 780 S I S K E R W V E T L V V A D T K M I E 260 TAC CAT GGG AGT GAG AAT GTG GAG TCC TAC ATC CTC ACC ATC ATG AAC ATG GTC ACT GGG 840 Y H G S E N V E S Y I L T I M N M V T G 280 TTG TTC CAT AAC CCA AGC ATT GGC AAT GCA ATT CAC ATT GTT GTG GTT CGG CTC ATT CTA 900 L F H N P S I G N A I H I V V V R L I L 300 CTC GAA GAA GAA GAG CAA GGA CTG AAA ATA GTT CAC CAT GCA GAA AAG ACA CTG TCT AGC 960 L E E E E Q G L K I V H H A E K T L S S 320 TTC TGC AAG TGG CAG AAG AGT ATC AAT CCC AAG AGT GAC CTC AAT CCT GTT CAT CAC GAC 1020 F C K W Q K S I N P K S D L N P V H H D 340 GTG GCT GTC CTT CTC ACC AGA AAG GAC ATC TGT GCT GGT TTC AAT CGC CCC TGC GAG ACC 1080 V A V L L T R K D I C A G F N R P C E T 360 CTG GGC CTG TCT CAC CTT TCA GGA ATG TGT CAG CCT CAC CGC AGT TGT AAC ATC AAT GAA 1140 L G L S H L S G M C Q P H R S C N I N E 380 GAT TCG GGA CTC CCT CTG GCT TTC ACA ATT GCC CAT GAG CTA GGA CAC AGC TTC GGC ATC 1200 D S G L P L A F T I A H E L G H S F G I 400 CAG CAT GAT GGG AAA GAA AAT GAC TGT GAG CCT GTG GGC AGA CAT CCG TAC ATC ATG TCC 1260 Q H D G K E N D C E P V G R H P Y I M S 420 CGC CAG CTC CAG TAC GAT CCC ACT CCG CTG ACA TGG TCC AAG TGC AGC GAG GAG TAC ATC 1320 R Q L Q Y D P T P L T W S K C S E E Y I 440 ACC CGC TTC TTG GAC CGA GGC TGG GGG TTC TGT CTT GAT GAC ATA CCT AAA AAG AAA GGC 1380 T R F L D R G W G F C L D D I P K K K G 460 TTG AAG TCC AAG GTC ATT GCC CCC GGA GTG ATC TAT GAT GTT CAC CAC CAG TGC CAG CTA 1440 L K S K V I A P G V I Y D V H H Q C Q L 480 CAA TAT GGA CCC AAT GCT ACC TTC TGC CAG GAA GTA GAA AAC GTC TGC CAG ACA CTG TGG 1500 Q Y G P N A T F C Q E V E N V C Q T L W 500 TGC TCC GTG AAG GGC TTT TGT CGC TCT AAG CTG GAC GCT GCT GCA GAT GGA ACT CAA TGT 1560 C S V K G F C R S K L D A A A D G T Q C 520 GGT GAG AAG AAG TGG TGT ATG GCA GGC AAG TGC ATC ACA GTG GGG AAG AAA CCA GAG AGC 1620 G E K K W C M A G K C I T V G K K P E S 540 ATT CCT GGA GGC TGG GGC CGC TGG TCA CCC TGG TCC CAC TGT TCC AGG ACC TGT GGG GCT 1680 I P G G W G R W S P W S H C S R T C G A 560 GGA GTC CAG AGC GCA GAG AGG CTC TGC AAC AAC CCC GAG CCA AAG TTT GGA GGG AAA TAT 1740 G V Q S A E R L C N N P E P K F G G K Y 580 TGC ACT GGA GAA AGA AAA CGC TAT CGC TTG TGC AAC GTC CAC CCC TGT CGC TCA GAG GCA 1800 C T G E R K R Y R L C N V H P C R S E A 600 CCA ACA TTT CGG CAG ATG CAG TGC AGT GAA TTT GAC ACT GTT CCC TAC AAG AAT GAA CTC 1860 P T F R Q M Q C S E F D T V P Y K N E L 620 TAC CAC TGG TTT CCC ATT TTT AAC CCA GCA CAT CCT TGT GAG CTC TAC TGC CGA CCC ATA 1920 Y H W F P I F N P A H P C E L Y C R P I 640 GAT GGC CAG TTT TCT GAG AAA ATG CTG GAT GCT GTC ATT GAT GGT ACC CCT TGC TTT GAA 1980 D G Q F S E K M L D A V I D G T P C F E 660 GGC GGC AAC AGC AGA AAT GTC TGT ATT AAT GGC ATA TGT AAG ATG GTT GGC TGT GAC TAT 2040 G G N S R N V C I N G I C K M V G C D Y 680 GAG ATC GAT TCC AAT GCC ACC GAG GAT CGC TGC GGT GTG TGC CTG GGA GAT GGC TCT TCC 2100 E I D S N A T E D R C G V C L G D G S S 700 TGC CAG ACT GTG AGA AAG ATG TTT AAG CAG AAG GAA GGA TCT GGT TAT GTT GAC ATT GGG 2160 C Q T V R K M F K Q K E G S G Y V D I G 720 CTC ATT CCA AAA GGA GCA AGG GAC ATA AGA GTG ATG GAA ATT GAG GGA GCT GGA AAC TTC 2220 L I P K G A R D I R V M E I E G A G N F 740 CTG GCC ATC AGG AGT GAA GAT CCT GAA AAA TAT TAC CTG AAT GGA GGG TTT ATT ATC CAG 2280 L A I R S E D P E K Y Y L N G G F I I Q 760 TGG AAC GGG AAC TAT AAG CTG GCA GGG ACT GTC TTT CAG TAT GAC AGG AAA GGA GAC CTG 2340 W N G N Y K L A G T V F Q Y D R K G D L 780 GAA AAG CTG ATG GCC ACA GGT CCC ACC AAT GAG TCT GTG TGG ATC CAG CTT CTA TTC CAG 2400 E K L M A T G P T N E S V W I Q L L F Q 800 GTG ACT AAC CCT GGC ATC AAG TAT GAG TAC ACA ATC CAG AAA GAT GGC CTT GAC AAT GAT 2460 V T N P G I K Y E Y T I Q K D G L D N D 820 GTT GAG CAG CAG ATG TAC TTC TGG CAG TAC GGC CAC TGG ACA GAG TGC AGT GTG ACC TGC 2520 V E Q Q M Y F W Q Y G H W T E C S V T C 840 GGG ACA GGT ATC CGC CGC CAA ACT GCC CAT TGC ATA AAG AAG GGC CGC GGG ATG GTG AAA 2580 G T G I R R Q T A H C I K K G R G M V K 860 GCT ACA TTC TGT GAC CCA GAA ACA CAG CCC AAT GGG AGA CAG AAG AAG TGC CAT GAA AAG 2640 A T F C D P E T Q P N G R Q K K C H E K 880 GCT TGT CCA CCC AGG TGG TGG GCA GGG GAG TGG GAA GCA TGC TCG GCG ACA TGC GGG CCC 2700 A C P P R W W A G E W E A C S A T C G P 900 CAC GGG GAG AAG AAG CGA ACC GTG CTG TGC ATC CAG ACC ATG GTC TCT GAC GAG CAG GCT 2760 H G E K K R T V L C I Q T M V S D E Q A 920 CTC CCG CCC ACA GAC TGC CAG CAC CTG CTG AAG CCC AAG ACC CTC CTT TCC TGC AAC AGA 2820 L P P T D C Q H L L K P K T L L S C N R 940 GAC ATC CTG TGC CCC TCG GAC TGG ACA GTG GGC AAC TGG AGT GAG TGT TCT GTT TCC TGT 2880 D I L C P S D W T V G N W S E C S V S C 960 GGT GGT GGA GTG CGG ATT CGC AGT GTC ACA TGT GCC AAG AAC CAT GAT GAA CCT TGC GAT 2940 G G G V R I R S V T C A K N H D E P C D 980 GTG ACA AGG AAA CCC AAC AGC CGA GCT CTG TGT GGC CTC CAG CAA TGC CCT TCT AGC CGG 3000 V T R K P N S R A L C G L Q Q C P S S R 1000 AGA GTT CTG AAA CCA AAC AAA GGC ACT ATT TCC AAT GGA AAA AAC CCA CCA ACA CTA AAG 3060 R V L K P N K G T I S N G K N P P T L K 1020 CCC GTC CCT CCA CCT ACA TCC AGG CCC AGA ATG CTG ACC ACA CCC ACA GGG CCT GAG TCT 3120 P V P P P T S R P R M L T T P T G P E S 1040 ATG AGC ACA AGC ACT CCA GCA ATC AGC AGC CCT AGT CCT ACC ACA GCC TCC AAA GAA GGA 3180 M S T S T P A I S S P S P T T A S K E G 1060 GAC CTG GGT GGG AAA CAG TGG CAA GAT AGC TCA ACC CAA CCT GAG CTG AGC TCT CGC TAT 3240 D L G G K Q W Q D S S T Q P E L S S R Y 1080 CTC ATT TCC ACT GGA AGC ACT TCC CAG CCC ATC CTC ACT TCC CAA TCC TTG AGC ATT CAG 3300 L I S T G S T S Q P I L T S Q S L S I Q 1100 CCA AGT GAG GAA AAT GTT TCC AGT TCA GAT ACT GGT CCT ACC TCG GAG GGA GGC CTT GTA 3360 P S E E N V S S S D T G P T S E G G L V 1120 GCT ACA ACA ACA AGT GGT TCT GGC TTG TCA TCT TCC CGC AAC CCT ATC ACT TGG CCT GTG 3420 A T T T S G S G L S S S R N P I T W P V 1140 ACT CCA TTT TAC AAT ACC TTG ACC AAA GGT CCA GAA ATG GAG ATT CAC AGT GGC TCA GGG 3480 T P F Y N T L T K G P E M E I H S G S G 1160 GAA GAA AGA GAA CAG CCT GAG GAC AAA GAT GAA AGC AAT CCT GTA ATA TGG ACC AAG ATC 3540 E E R E Q P E D K D E S N P V I W T K I 1180 AGA GTA CCT GGA AAT GAC GCT CCA GTG GAA AGT ACA GAA ATG CCA CTT GCA CCT CCA CTA 3600 R V P G N D A P V E S T E M P L A P P L 1200 ACA CCA GAT CTC AGC AGG GAG TCC TGG TGG CCA CCC TTC AGC ACA GTA ATG GAA GGA CTG 3660 T P D L S R E S W W P P F S T V M E G L 1220 CTC CCC AGC CAA AGG CCC ACT ACT TCC GAA ACT GGG ACA CCC AGA GTT GAG GGG ATG GTT 3720 L P S Q R P T T S E T G T P R V E G M V 1240 ACT GAA AAG CCA GCC AAC ACT CTG CTC CCT CTG GGA GGA GAC CAC CAG CCA GAA CCC TCA 3780 T E K P A N T L L P L G G D H Q P E P S 1260 GGA AAG ACG GCA AAC CGT AAC CAC CTG AAA CTT CCA AAC AAC ATG AAC CAA ACA AAA AGT 3840 G K T A N R N H L K L P N N M N Q T K S 1280 TCT GAA CCA GTC CTG ACT GAG GAG GAT GCA ACA AGT CTG ATT ACT GAG GGC TTT TTG CTA 3900 S E P V L T E E D A T S L I T E G F L L 1300 AAT GCC TCC AAT TAC AAG CAG CTC ACA AAC GGC CAC GGC TCT GCA CAC TGG ATC GTC GGA 3960 N A S N Y K Q L T N G H G S A H W I V G 1320 AAC TGG AGC GAG TGC TCC ACC ACA TGT GGC CTG GGG GCC TAC TGG AGA AGG GTG GAG TGC 4020 N W S E C S T T C G L G A Y W R R V E C 1340 AGC ACC CAG ATG GAT TCT GAC TGT GCG GCC ATC CAG AGA CCT GAC CCT GCA AAA AGA TGC 4080 S T Q M D S D C A A I Q R P D P A K R C 1360 CAC CTC CGT CCC TGT GCT GGC TGG AAA GTG GGA AAC TGG AGC AAG TGC TCC AGA AAC TGC 4140 H L R P C A G W K V G N W S K C S R N C 1380 AGT GGG GGC TTC AAG ATA CGC GAG ATT CAG TGC GTG GAC AGC CGG GAC CAC CGG AAC CTG 4200 S G G F K I R E I Q C V D S R D H R N L 1400 AGG CCA TTT CAC TGC CAG TTC CTG GCC GGC ATT CCT CCC CCA TTG AGC ATG AGC TGT AAC 4260 R P F H C Q F L A G I P P P L S M S C N 1420 CCG GAG CCC TGT GAG GCG TGG CAG GTG GAG CCT TGG AGC CAG TGC TCC AGG TCC TGT GGA 4320 P E P C E A W Q V E P W S Q C S R S C G 1440 GGT GGA GTT CAG GAG AGA GGA GTG TTC TGT CCA GGA GGC CTC TGT GAT TGG ACA AAA AGA 4380 G G V Q E R G V F C P G G L C D W T K R 1460 CCC ACA TCC ACC ATG TCT TGC AAT GAG CAC CTG TGC TGT CAC TGG GCC ACT GGG AAC TGG 4440 P T S T M S C N E H L C C H W A T G N W 1480 GAC CTG TGT TCC ACT TCC TGT GGA GGT GGC TTT CAG AAG AGG ACT GTC CAA TGT GTG CCC 4500 D L C S T S C G G G F Q K R T V Q C V P 1500 TCA GAG GGC AAT AAA ACT GAA GAC CAA GAC CAA TGT CTA TGT GAT CAC AAA CCC AGA CCT 4560 S E G N K T E D Q D Q C L C D H K P R P 1520 CCA GAA TTC AAA AAA TGC AAC CAG CAG GCC TGC AAG AAA AGT GCC GAT TTA CTT TGC ACT 4620 P E F K K C N Q Q A C K K S A D L L C T 1540 AAG GAC AAA CTG TCA GCC AGT TTC TGC CAG ACA CTG AAA GCC ATG AAG AAA TGT TCT GTG 4680 K D K L S A S F C Q T L K A M K K C S V 1560 CCC ACC GTG AGG GCT GAG TGC TGC TTC TCG TGT CCC CAG ACA CAC ATC ACA CAC ACC CAA 4740 P T V R A E C C F S C P Q T H I T H T Q 1580 AGG CAA AGA AGG CAA CGG TTG CTC CAA AAG TCA AAA GAA CTC TAA 4785 R Q R R Q R L L Q K S K E L * 1595