protein tyrosine phosphatase, non-receptor type 11

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Src homology-2 domain-containing protein tyrosine phosphatase involved in growth factor and cytokine-dependent intracellular signal transduction regulating multiple processes [Pubmed]; WT and E76K mutant PTPN11 dephosphorylates SRC phosphorylated KRAS WT and G12V mutant, thereby enhancing RAF binding to RAS [Pubmed]

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