PBX1

pre-B-cell leukemia transcription factor 1

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function summary function summary

promotes chromatin openness at specific genomic locations through its capacity to read specific epigenetic signatures, accordingly, PBX1 guides ER_ recruitment to a specific subset of sites, breast cancer cells depleted of PBX1 do not proliferate following estrogen stimulation [Pubmed]

Suppresses Gene name Field Field Promotes