B-cell CLL/lymphoma 11B (CTIP2)

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function summary function summary

Zn-finger transcription factor reqiured for diferentiation of T lymphocytes [Pubmed]; inhibits HDM2 (ubiquitin ligase for p53) expression in a p53-dependent manner [Pubmed]; acts as a transcriptional repressor and it's upregulation by EWS-FLI fusion oncogene is necessary for the maintenance of the transformed phenotype in Ewing sarcoma [Pubmed]

Suppresses Gene name Field Field Promotes