This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Pilot: DEAD box proteins
- Study ID
- This group of genes encode proteins which have a DEAD box domain, so called because of a highly conserved Asp-Glu-Ala-Asp motif. These proteins are involved in ATP-dependent, nucleic-acid unwinding and are putative RNA helicases. They have been implicated in processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Translocations of DEAD box genes have been reported in NHL and AML.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples