This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Pilot: Inositol Polyphosphate Phosphatases
- Study ID
- The inositol polyphosphate phosphatase family members hydrolyse phosphates from phosphatidylinositol signalling pathway molecules, thereby affecting function of multiple signalling pathways involved in growth and differentiation. These signalling pathways are deregulated via known mutations in both the PTEN and PIK3CA genes in human cancer.The samples in this study are a set of cancer cell lines that all have a matched normal cell line. All of the mutations are confirmed as somatic.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples