This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Pilot: High mobility group proteins - DNA binding
- Study ID
- High mobility group (HMG) proteins are a family of relatively low molecular weight non-histone components in chromatin. They bind DNA and are thought to be involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. Translocations of HMG genes have been found in follicular thyroid adenoma and various mesenchymal neoplasms.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples