This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Pilot: Heat shock proteins
- Study ID
- Heat shock protein proteins (HSPs) are so called because of the up regulation in their expression when cells are exposed to stress like heat, cold, toxins and hypoxia. In addition to their role in the stress response, HSPs also act as chaperones mediating normal protein folding, trafficking and degradation. HSPs have also been associated with functions as diverse as initiation of translation, controlling apoptosis and mediating the immune response. This group of genes code for many HSPs including DNAJ (HSP40) homologues and other associated proteins. HSP genes are involved in translocations in NHL.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples