This tab shows an overview of the selected study/paper [more details]
Study
Glioblastoma Multiforme (TCGA) data import from ICGC
Study Id
COSU329
Description
The International Cancer Genome Consortium is a global effort with the primary goal of generating and freely distributing a comprehensive catalogue of the genomic abnormalities underlying 50 different cancer types. All the validated Simple Mutations in this release have been recovered from the Data Coordination Center (DCC) and curated into COSMIC.

In 2008, The Cancer Genome Atlas (TCGA) announced their first results of screening 91 Glioblastoma tumours through a set of 601 candidate genes (Pubmed), with an additional data release some months later on the TCGA data portal. This study comprises additional mutation data from these samples, after the initial two pilot phases of this project.
Genes Analysed
12464
Mutated Samples
374
Total No. of Samples
515
This tab shows the correlation plot between top 20 genes and samples [more details]
This tab shows genes with mutations in the selected study/paper [more details]
Genes Samples CDS Mutation AA Mutation
This tab shows genes without mutations in the selected study/paper [more details]
Non-Mutant Genes Gene Id (COSG)
This tab shows samples without mutations in the selected study/paper [more details]
Non-Mutant Samples Sample Id (COSS)
This tab shows mutated samples in the selected study/paper [more details]
Sample Name Mutation Count
This tab shows non coding variant in the selected study/paper [more details]
Sample ID Sample Name ID NCV Annotation Zygosity Chromosome Genome start Genome stop Genome version Strand WT seq Mut seq
This tab shows the gene expression and copy number variation data for this study. [more details]

Table Information

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The table currently shows only high value (numeric) copy number data. Copy number segments are excluded if the total copy number and minor allele values are unknown.

Click here to include all copy number data. For more detailed information about copy number data and gain/loss definitions click here.

Sample Gene Expression Expr Level (Z-Score)

Over Expressed; Z-Score > 2.0

Under Expressed; Z-Score < -2.0

Normal; Z-Score within the range -2.0 to 2.0

CN Type Minor Allele Copy Number CN Segment Posn. Average Ploidy

1. N/A represents cases where the average ploidy value is not available( mostly ICGC samples). For some TCGA samples where the minor allele information is not available the average ploidy value could not be calculated.

2. For TCGA samples, the ASCAT algorithm was used to calculate the average ploidy.

3. For CGP samples, the PICNIC algorithm was used to calculate the average ploidy.

CNV
This tab shows the fusion mutations observed in this sample [more details]
Gene Sample Name Id Sample(COSS) CDS Mutation Somatic status Zygosity Validated Type