This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Renal: Downstream of kinase family.
- Study ID
- Docking proteins (DOK) interact with receptor tyrosine kinases and mediate particular biological responses. Each of the DOK proteins is involved in different cellular signalling pathways. DOK3 is a negative regulator of JNK signaling in B-cells while DOK1 appears to be a negative regulator of the insulin signaling pathway and DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples