This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Renal: Apoptosis genes
- Study ID
- Apoptosis (programmed cell death) is a key process in managing cellular responses to various kinds of damage and regulating tissue homeostasis. Abrogation of these pathways results in cells that continue to divide despite critical DNA damage. Several genes involved in apoptosis have been shown to be mutated in human cancers and damage sensor/responder pathways triggering apoptosis are frequently aberrant in cancer. These results are derived from those genes either directly or indirectly implicated in apoptosis.
The samples in this study are a set of cancer cell lines that all have a matched normal cell line. All of the mutations are confirmed as somatic.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples