This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Renal: ADAM metallopeptidase family
- Study ID
- ADAMs are transmembrane proteins that contain a disintegrin and a metallopeptidase domain. The ADAM gene family has multiple members and have been implicated in a variety of biological processes including cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. ADAM10 is responsible for the proteolytic release of several cell-surface proteins including TNF-alpha, ephrin-A2 and Notch. This gene set comprises ADAM and ADAM-like proteins.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples