This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Pilot: Arachidonate metabolism and phospholipase A2 family.
- Study ID
- This gene set is comprised of arachidonate lipoxygenase and phospholipase A2 genes which are involved in the metabolism of arachidonate. Phospholipase A2 is responsible for the release of arachidonic acid from membrane phospholipids allowing its subsequent conversion to leukotrienes and prostaglandins which form part of the inflammatory response. Arachidonate lipoxygenases are lipid peroxidating enzymes implicated in the pathogenesis of inflammatory disorders and carcinogenesis and are also involved in leukotriene metabolism.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples