This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Pilot: Mps One Binder kinase activator-like.
- Study ID
- This gene set is comprised of the human homologues of the yeast Mps one binder kinase activator proteins. The yeast proteins interact with a serine threonine kinase important in regulating cytokinesis and mitotic exit. Human MOB proteins have been found to interact with human NDR proteins which are serine threonine kinases implicated in cell proliferation and tumour progression. Increased MOB2/HCCA2 expression has been associated with hepatocellular carcinoma.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples