This section shows a general overview of information for the selected study (COSU identifier) or publication (COSP identifier). Studies may have been performed by the WTSI Cancer Genome Project, or imported from the ICGC/TCGA. You can see more information on the help pages.
- Pilot: SMAD protein family
- Study ID
- The SMAD family of genes are human homologues of the drosophila gene Mothers against decepentaplegic (MAD). SMADs are transcription factors which modulate the cell growth regulatory activity of TGF?. Somatic mutations in one of these genes (MADH4) have been found in colorectal, intestinal and pancreatic cancers.
Sequencing of any given sample through the gene sets should be considered work in progress. Lack of reported mutations in any given gene for a particular sample does not necessarily imply the sample is wildtype for the gene.
- Genes Analysed
- Mutated Samples
- Total No. of Samples