The Histogram tab shows a graphical representation of the mutations observed in the selected gene. The Filters panel on the right hand side of the page shows the current gene and other selections. [more details]

Note: In some web browsers, the Genome Browser may display a blank white content panel when switching back from another tab. If this happens please click and drag the blank content panel. [ Full screen view ]

Loading sample Genome browser
This tab displays a table of primary tissues with histogram showing percentage of mutated samples for both point and CNV data. Mouseover the histogram to see more data. [more details]
This tab displays pie charts and graphs, which show the distribution of mutation types for the selected gene. [more details]
This tab shows publications associated with the selected gene. [more details]
Reference Title Author Year Journal Status COSMIC Pubmed
This tab shows a graphical representation of the selected gene in JBrowse and a general overview of the information available for the gene. [more details]
Gene name
KRT86
Genomic Coordinates
12:52301917..52308585
Gene Id
COSG74820
Synonyms
FLJ25176, HB6, Hb1, KRTHB1, KRTHB6, MNX, hHb6, CCDS41785.1, O43790 more
A8K872, Q6YFL2, Q6YFL4, Q8N120, Q8NFV0, Q8NFV1, Q9NSB0, ENSG00000170442
No.of Samples
Total number of unique samples: 29049
Unique samples with mutations: 71
cDNA Sequence
ENST00000293525
Protein Sequence
KRT86
Transcript and Protein Aligned
ENST00000293525+KRT86
OMIM:
601928
Transcript:
ENST00000293525
Genome Browsers:
Ensembl, UCSC
Copy Number:
CONAN
CCDS:
CCDS41785.1
Pfam:
O43790
TrEMBL:
A8K872
HGNC:
6463

This tab displays a table of mutations for the selected gene. [more details]
Position (AA) Mutation (CDS) Mutation (Amino Acid) Mutation ID (COSM) Count Mutation Type

This tab displays a table of fusions for the selected gene. [more details]
Position Mutation (CDS) Mutation (Amino Acid) Mutation ID (COSF) Count Mutation Type

This tab shows a table of gene expression and copy number variation (CNV) data for the selected gene with links to Sample, Study, CNV and (icons) to the ChromoView page (to view CNVs across the whole chromosome), the COSMIC Genome Browser and Ensembl. [more details]

Table Information

Hide

The table currently shows only high value (numeric) copy number data. Copy number segments are excluded if the total copy number and minor allele values are unknown.

Click here to include all copy number data. For more detailed information about copy number data and gain/loss definitions click here.

Sample Expression Expr Level (Z-Score)

Over Expressed; Z-Score > 2.0

Under Expressed; Z-Score < -2.0

Normal; Z-Score within the range -2.0 to 2.0

CN Type Minor Allele Copy Number CN Segment Posn. Average Ploidy

1. N/A represents cases where average ploidy value is not available( mostly ICGC samples). For some TCGA samples where minor allele information is not available the average ploidy value could not be calculated.

2. For TCGA samples, Ascat algorithm is used to calculate the average ploidy.

3. For CGP samples, Picnic algorithm is used to calculate the average ploidy.

Study CNV

This page contains the complete Methylation data for the gene and filter selection(s). Each Methylation probe links to the COSMIC Genome Browser and Ensembl. [more details]
Sample Name Sample ID Probe ID Probe Posn. Type

High (Hypermethylation); Beta-Value > 0.8 and differs from normal average by > 0.5

Low (Hypomethylated); Beta-Value < 0.2 and differs from normal average by > 0.5

Level (Beta-Value) Normal Average Study

Filters

    • Start
    • End
    • cDNA
    • Amino Acid
    • NS Biliary tract Breast Central nervous system Cervix Endometrium Haematopoietic and lymphoid Kidney Large intestine Liver Lung Oesophagus Ovary Pancreas Prostate Skin Stomach Thyroid Upper aerodigestive tract Urinary tract
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    • Note: After making your selection(s) please close this window and click 'Apply' in the filters panel.
    • Genome View
      Many probes fall outside of coding regions and are not displayed on the Histogram. To view all methylation probes within or in close proximity to KRT86 please use the COSMIC Genome Browser